NCCN: Cancer Drug Shortages Remain a Challenge for Clinicians
89 percent of cancer centers report that cancer drugs are in short supply, most often vinblastine, etoposide, and topotecan
Precision-Guided Treatment Improves Outcomes for High-Risk Pediatric Cancer
Improvement in two-year progression-free survival seen with PGT versus standard of care or targeted agents not guided by molecular findings
Survival Improves With Open Hysterectomy for Cervical Cancer
Lower rate of disease-free survival and overall survival seen for minimally invasive versus open hysterectomy
Guidelines Address RT for Management of HPV-Linked Oropharyngeal Cancer
Tailored recommendations presented to maximize survival and minimize side effects
Immunoglobulin Replacement Therapy Beneficial for Blood Cancers
Reduction seen in hypogammaglobulinemia, infections or severe infections, and associated antimicrobial use
PIK3CA Could Guide Use of COX-2 Inhibitors in Treatment for Colon Cancer
Patients with stage III resected colon cancer with PIK3CA gain-of-function mutations treated with celecoxib had improved DFS, OS
Glofitamab + GemOx Superior to Rituximab + GemOx for Lymphoma
Significant overall survival benefit seen for Glofit-GemOx at primary and follow-up analysis
Acupuncture Reduces Endocrine Symptoms, Hot Flashes in Breast Cancer
Significant improvement seen in endocrine symptom subscale score, hot flash score, FACT-Breast total score
Nonsignificant Survival Benefit Seen for Dabrafenib, Trametinib in Melanoma
Consistent survival benefit seen across several prespecified subgroups, including those with a BRAF V600E mutation
Posttransplant Cyclophosphamide GVHD Prophylaxis Beneficial in Leukemia
PTCy GVHD prophylaxis after allogeneic stem cell transplant yields comparable relapse incidence, lower GVHD
