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Young black women have a higher rate of BRCA1 or BRCA2 gene mutations than previously believed

Higher Frequency of BRCA Mutations Seen in Black Women

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In study of those under 50 with invasive form of disease, 12 percent had BRCA1, BRCA2 mutations
Many elderly oncology patients use complementary and alternative medications

Many Elderly Oncology Patients Taking Alternative Medicines

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Associated with polypharmacy, vision impairment, and urologic comorbidities
For most atrial fibrillation patients taking warfarin who require temporary interruption for a procedure

Periop Bridging Unnecessary for Most A-Fib Patients on Warfarin

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Arterial thromboembolism risk doesn't appear to rise without additional drug treatment
Longer colonoscopy withdrawal time is associated with lower risk for colorectal cancer over five years

Longer Colonoscopy Withdrawal Time May Cut Cancer Risk

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Viewing time of less than six minutes linked to higher cancer rates
A proposal for identifying lower-cost generic biotech drugs has been released by the U.S. Food and Drug Administration.

FDA Issues Proposal on Lower-Cost, Generic Biotech Drugs

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All biotech drugs to carry a four-letter code to distinguish brand name, generic versions
Excision repair cross-complementing group 1 genotype for the single nucleotide polymorphism cytosine-to-thymine substitution at codon 118 interacts with post-radiotherapy plasma Epstein-Barr virus DNA to identify favorable prognosis for a subgroup of patients with nasopharyngeal carcinoma

ERCC1 SNP Can Identify Good Prognosis in Nasopharyngeal CA

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ERCC1 C118T genotype may identify good prognosis in subgroup of pEBV-negative patients
An experimental blood test may one day detect the return of early-stage breast cancer months before it is revealed by computed tomography or magnetic resonance imaging

Blood Test Predicts Relapse in Early-Stage Breast Cancer

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Circulating tumor DNA analysis spots stray cells months before scans detect recurrence
Daratumumab monotherapy has a favorable safety profile and encouraging efficacy in patients with heavily pretreated and refractory myeloma in a phase 1-2 trial. The results of the study were published online Aug. 26 in the New England Journal of Medicine.

Daratumumab Monotherapy Promising for Multiple Myeloma

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Findings in a phase 1-2 study of patients with relapsed myeloma or relapsed/refractory myeloma
For adult patients with de novo acute myeloid leukemia

Genomic Approach Could Aid Risk Stratification in Adults With AML

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Persistent leukemia-linked mutations in remission samples tied to increased relapse, worse survival
A majority of women who receive false positives on mammography experience distress and anxiety

Most Women Feel Distress With False-Positive Mammogram

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Majority had issues such as anxiety, sleeplessness, often persisting long after being declared cancer-free