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Pathogenic germline mutations are common in women with ovarian

Inherited Mutations in 18 Percent With Ovarian Cancer

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Mutations seen in BRCA1/2, DNA mismatch repair genes, other suspected/established risk genes
For patients with metastatic castration-resistant prostate cancer

ASCO: CTC Heterogeneity Predicts Hormone Tx Response in mCRPC

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Patients with higher heterogeneity score did not respond well to hormone therapy
Adult survivors of childhood cancer are at increased risk for subclinical cardiovascular disease

Considerable Subclinical Cardiac Disease in Childhood CA Survivors

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Exposure to anthracycline and heart radiation tied to higher odds
For patients with chronic conditions

Many Patients Using E-Mail As First Method of Provider Contact

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Online communications reduced need for phone calls and office visits for many
For men with prostate cancer

ASCO: Aspirin Use Linked to Lower Risk of Lethal Prostate CA

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Risk of prostate cancer mortality reduced with regular aspirin use after diagnosis
Having an identical twin diagnosed with cancer increases the other twin's risk of developing not just that type but any form of cancer

Researchers Calculate Family Risk Estimates for Cancer

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Estimated 33 percent of overall risk is genetic; certain types of cancer have additional risk
For women with breast cancer treated with primary systemic chemotherapy

Axillary pCR Linked to Improved Breast Cancer Survival

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Very high survival for axillary pathologic complete response for women with HER2-positive disease
For patients with advanced renal cell carcinoma

ASCO: Cabozantinib Improves Progression-Free Survival in RCC

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Improvements seen across patient subgroups defined by risk category, tumor burden, prior therapy
Initial diagnostic characteristics may be able to identify men initiating active surveillance who could avoid confirmatory biopsy

Diagnostic Factors May Help Patients Avoid Prostate Biopsy

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Prostate-specific antigen density, total tumor length are significant predictors
β-genus human papillomavirus is a risk factor for cutaneous squamous cell carcinoma in otherwise healthy individuals

β-Genus Human Papillomavirus Poses Skin Cancer Risk

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HPV subtypes 5, 8, 17, 20, and 38 tied to significant increased risk