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For patients with Fabry's disease

Tx Response No Different for Migalastat, Placebo in Fabry’s

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Percentage of patients with response at six months doesn't differ with migalastat, placebo treatment
For patients with estrogen receptor-positive metastatic breast cancer

ESR1 Mutations Tied to Worse Survival in Metastatic Breast CA

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ESR1 mutations prevalent in ER-positive metastatic breast cancer and linked to shorter survival
Overall

Many U.S. Hospitals Offer Language Services

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Percentage of hospitals offering language services increases with level of need
Opioid abuse arises in only a very small fraction -- less than half of 1 percent -- of cases involving surgical patients aged 65 or older

Risk of Post-Op Opioid Abuse Deemed Low for Elderly Patients

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Vast majority of patients use the meds short term to ease their pain
Guidelines have been developed for neoadjuvant chemotherapy use for newly diagnosed

Recs Developed for Neoadjuvant Chemo in Ovarian Cancer

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Guidance provided for clinicians treating women with stage IIIC or IV epithelial ovarian cancer
Overweight and obese women who eat a Western-style diet may develop more dense breast tissue

Western Diet May Contribute to Dense Breasts

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In study, women who ate such a diet also had 46 percent higher risk of breast cancer
The levels of polyfluoroalkyl and perfluoroalkyl substances in drinking water exceed government-recommended safety levels for at least six million people in the United States

Many Americans Exposed to Toxic Chemicals in Drinking Water

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Immunotoxicity of polyfluoroalkyl/perfluoroalkyl substances seen at current exposure levels
More attention should be given to frailty-related items in clinical practice guidelines for nonmelanoma skin cancer

Guidance Needed for Frail Elderly With Nonmelanoma Skin Cancer

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Integration of frailty-related items into current guidelines on nonmelanoma skin cancer is limited
For certain patients with metastatic renal cell carcinoma

Active Surveillance Prior to Systemic Tx Feasible in Renal CA

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Shorter surveillance period for those with more IMDC adverse risk factors, more metastatic disease sites
Tumor cell-intrinsic metabolic factors may contribute to anti-programmed death 1 (PD-1)/PD-L1 treatment resistance in renal cell carcinoma

Metabolic Factors May Contribute to Tx Resistance in Renal Cancer

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Genes involved in metabolic and solute transport function linked to treatment failure in PD-L1+ RCC