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Long-term proton pump inhibitor use is associated with increased risk of fundic gland polyps

Review Links PPI Use With Risk of Fundic Gland Polyps

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Proton pump inhibitor therapy may also be associated with increased risk of gastric cancer
Privately insured Americans spent nearly 5 percent more on health care last year than in 2014; this increase was significantly more than that seen in previous years and reflects higher costs for prescription drugs

Rising Rx, ER Prices Pushing U.S. Health Care Spending Up

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Prescription drugs are the fastest growing expense, report shows
Octamer-binding transcription factor 4 is a predictive marker for patients with digestive system cancers

Oct4 Found to Be a Prognostic Marker for Digestive Cancers

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Elevated Oct4 levels tied to poor overall, disease-free, and recurrence-free survival
Patients with muscle invasive bladder cancer who undergo neoadjuvant chemotherapy before and after radical cystectomy frequently experience thromboembolic events

Thromboembolic Events Common With Chemo for Bladder Cancer

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Findings in patients with muscle invasive bladder cancer who undergo neoadjuvant chemotherapy
Discussing the risk of long-term opioid use disorder with patients is associated with reduced misuse of opioids

Discussing Opioid Risks With Patients Reduces Misuse

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Sixty percent lower rate of saving of pills among patients who talked to their doctor about risks
Circulating exosomes released under intermittent hypoxia conditions

Intermittent Hypoxia Promotes Lung Tumor Cell Aggressiveness

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IH-induced exosomes from mice significantly promote TC1 malignant properties
Clinicians should not screen for thyroid cancer in patients who have no symptoms of the disease

USPSTF Continues to Recommend Against Thyroid Cancer Screening

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Widespread routine thyroid cancer screening can lead to overdiagnosis, overtreatment
Men treated with implantable testosterone pellets have a statistically significant increase in mean hematocrit

Small Increase in Hematocrit With Implantable Testosterone

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Statistically significant 2.2 percent increase in mean hematocrit unlikely to be clinically relevant
An updated index incorporating gene and molecular alterations can predict survival in non-small-cell lung cancer with brain metastases

Updated Index Predicts Survival in NSCLC With Brain Metastases

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Significant prognostic factors include four factors from earlier index, plus EGFR and ALK alterations
Insulin resistance assessed by homeostasis model assessment index correlates with the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus infection

HOMA2-IR Tied to Hepatocellular Carcinoma Risk in Hepatitis B

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HOMA2-IR independently linked to HCC in patients without overt metabolic abnormalities