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HPV16 DNA detected in fine-needle aspirations from neck masses is a reliable indicator for diagnosis of an HPV-positive oropharyngeal squamous cell carcinoma

HPV16 DNA From Fine-Needle Aspirations OK for Diagnosis

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Presence of HPV16 DNA is strong indicator of HPV-positive oropharyngeal cancer
The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent

Depression, Suicide Ideation Prevalent in Medical Students

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Prevalence of depression or depressive symptoms is 27.2 percent; suicide ideation, 11.1 percent
Breast cancer survivors who undergo multimodal treatment have higher cytokines and comorbidities than controls without cancer

Multimodal Breast Cancer Tx May Up Cytokines, Comorbidities

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Breast cancer survivors treated with multimodalities have greater burden of comorbid conditions
Methodological concerns have limited the analysis of saliva-based biomarkers for oral squamous cell carcinoma

Review: Methodological Limitations for OSCC Biomarkers

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Limitations include lack of methodological criteria within studies, lack of consensus on marker choices
A proposed biosimilar is comparable to trastuzumab for women with ERBB2-positive metastatic breast cancer

Biosimilar Promising for ERBB2+ Breast Cancer Treatment

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Equivalent response rate for women with ERBB2-positive metastatic breast cancer receiving taxanes
High-dose crizanlizumab treatment is associated with a significantly lower rate of sickle cell-related pain crises than placebo

ASH: Lower Rate of Sickle Cell Pain Crises With Crizanlizumab

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Lower rate of crises per year; longer median time to first, second crises with high-dose therapy
For patients with human epidermal growth factor receptor 2-overexpressing early breast cancer

Meds Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

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However, perindopril, bisoprolol do protect against declines in LVEF in HER2-positive early breast cancer
Alcohol intake is associated with increased risk of melanoma

Alcohol Intake Linked to Increase in Risk of Melanoma

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Correlation stronger for melanoma in relatively UV-spared sites versus UV-exposed sites
Cancer survivors with ST-segment elevation myocardial infarction have increased acute in-hospital and long-term noncardiac mortality risk but no increased acute or long-term cardiac mortality risk with guideline-recommended cardiac care

Acute, Noncardiac Mortality Risk Up for CA Patients With STEMI

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But no increased acute or long-term cardiac mortality risk with guideline-recommended cardiac care

November 2016 Briefing – Hematology & Oncology

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Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for November 2016. This roundup includes...