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For patients who received transfusions in Sweden and Denmark from 2003 to 2012

No Link for Transfused Red Blood Cell Storage, Mortality

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No link for length of red blood cell storage, mortality in transfusion recipients from Sweden, Denmark
The Drug Enforcement Administration has announced critical changes in its registration renewal process

DEA Announces Critical Changes in Registration Renewal Process

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The ability to renew a registration online after the expiration date will no longer be available
The drug Rubraca (rucaparib) has been granted accelerated approval by the U.S. Food and Drug Administration to treat advanced ovarian cancer.

FDA Grants Fast-Track Approval to Ovarian Cancer Drug

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Rubraca's use is specific to women with deleterious BRCA mutations
For superficial or nodular basal cell carcinoma at low-risk sites

Imiquimod Has Sustained Benefit for Basal Cell Carcinoma

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Lower treatment success for imiquimod 5 percent than surgery, but rates similar at three, five years
As many as one in six colorectal cancer patients under the age of 50 have genetic traits that greatly increase the risk of cancer

CRC in Patients Under 50 Often Caused by Genetic Mutations

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One in six diagnosed under 50 have at least one gene mutation that ups risk of cancer
The rate of germline BRCA1/2 and ATM mutations is significantly higher among patients with lethal prostate cancer and is an independent predictor of lethal prostate cancer

BRCA1/2, ATM Mutations ID Risk for Lethal Prostate Cancer

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After adjustment for covariates, mutation carrier remained independent predictor of lethal PCa
Magnetic resonance imaging (MRI) and MRI-targeted biopsies have a role in the diagnosis and treatment of patients with a prior negative prostate biopsy

MRI Has a Role to Play After Negative Prostate Biopsy

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Magnetic resonance imaging, MRI-targeted biopsy facilitate detection of clinically significant disease
The Society for Industrial and Organizational Psychology Ototoxicity Scale seems to be best for classifying ototoxicity in cisplatin-treated pediatric patients

SIOP Scale Best for Detecting Ototoxicity With Cisplatin Tx

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Findings show superiority for SIOP in pediatric patients with planned cisplatin-containing treatment
Loss of argininosuccinate synthetase 1

ASS1 Loss Identified in Invasive Bladder Cancer

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ASS1-deficient cells were preferentially sensitive to ADI-PEG 20, as shown by reduced cell viability
For patients with squamous cell carcinoma

Microsurgical Head and Neck Reconstruction Is Cost-Effective

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Cost-effective versus locoregional flaps for all stages of SCC, especially in early-stage cancer