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The median cost of cancer drug development is $648.0 million

Median Cost of Cancer Drug Development $648.0 Million

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Total revenue from sales of 10 drugs was $67.0 billion, with total R&D spending of $7.2 billion
Zika virus is an oncolytic virus that preferentially targets glioblastoma stem cells

Zika Virus Preferentially Targets Glioblastoma Stem Cells

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ZIKV preferentially infects, kills GSCs relative to differentiated tumor progeny, normal neuronal cells
Neurological complications associated with anti-programmed death 1 antibody treatment have a diverse phenotype

Diverse Neurological Effects Linked to Anti-PD-1 Therapy

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Complications seen after median of 5.5 cycles of anti-PD-1-inhibitors; include myopathy, neuropathies
From 2009-2010 to 2013-2014 there was a decrease in the prevalence of vaccine-type human papillomavirus among unvaccinated young women aged 18 to 26 years

Vaccine-Type HPV Rates Down for Unvaccinated Young Women

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Significant decrease among unvaccinated women aged 18 to 26 years from 2009-2010 to 2013-2014
There is strong evidence that physical activity and a healthy diet reduce the risk of colorectal cancer

Strong Evidence for Healthy Lifestyle Reducing CRC Risk

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Consuming whole grains, foods with dietary fiber, dairy products reduces risk of colorectal cancer
For men with prostate cancer there is no difference in acute genitourinary or sexual dysfunction between 6- and 2-fraction high-dose-rate brachytherapy monotherapy

No Difference in Toxicity for 6-, 2-Fraction HDR in Prostate Cancer

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Urinary, sexual toxicity similar with 6-, 2-fraction high-dose-rate brachytherapy regimen
Outcomes of treatment with third-generation CAR T-cell therapy in CD19-positive B-cell malignancy are associated with patients' immune status

Immune Status Tied to Outcomes in Third-Gen CAR T-Cell Therapy

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In leukemia/lymphoma, after treatment CD19-targeting chimeric antigen receptor T-cell therapy
Injection of inactivated modified vaccinia virus Ankara into tumors is effective and generates antitumor immunity

Inactivated Vaccinia Virus Shows Promise Against Advanced Cancer

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Combined with immune checkpoint blockade therapy, iMVA generates synergistic antitumor effects
Mailed outreach invitations offering a fecal immunochemical test (FIT) or colonoscopy increase the proportion of participants completing colorectal cancer screening

Mailed Invitations Increase CRC Screening Completion

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And providing specific reminders to general practitioners improves participation in FIT screening
Universal sequencing of a broad panel of cancer-related genes is associated with increased detection of potentially clinically significant heritable mutations

Universal Sequencing of Cancer Genes Ups Mutation Detection

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Increased detection of heritable mutations over the predicted yield of testing based on guidelines