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The fibroblast growth factor receptor 3 transforming acidic coiled-coil containing protein 3 (TACC3) gene fusion recruits endogenous TACC3 away from the mitotic spindle

New Link Seen Between Gene Fusion and Bladder Cancer

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Previously overlooked section of fusion found to negatively impact cancer cells, researchers say
Programmed death-ligand 1 is primarily expressed in metastatic colorectal cancer lesions

PD-L1 Mainly Expressed in Metastatic CRC Lesions

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Overall, 81.8 percent of metastatic CRCs and 40.9 percent of primary lesions had PD-L1 expression
For people living with HIV

Expected Burden of Lung Cancer High for People Living With HIV

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PLWH who adhere to antiretroviral tx but smoke are substantially more likely to die from lung cancer
Spin in biomedical literature (also referred to as "science hype") is prevalent

‘Science Spin’ Found Prevalent in Biomedical Literature

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Nature of spin varies, with highest variability in prevalence of spin seen in trials
Aliqopa (copanlisib) has been approved by the U.S. Food and Drug Administration to treat adults with relapsed follicular lymphoma who have received at least two prior treatments with certain other drugs.

FDA Approves Aliqopa for Follicular Lymphoma

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Aliqopa, a kinase inhibitor, blocks several enzymes that promote cell growth
Sepsis is present in 6 percent of adult hospitalizations

EHR Data May Beat Claims Data in Assessing Sepsis Incidence

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Based on clinical data, no change seen in incidence of sepsis, combined outcome of death or discharge
Physicians spend almost six hours per day in the electronic health record

Doctors Spend Almost Six Hours Per Day on EHR Tasks

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Clerical and administrative tasks including order entry, billing account for almost half of hours
Solar occupational ultraviolet exposure is a major determinant of incident squamous cell carcinoma

Skin Cancer Prevention Strategies Needed in Work Settings

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High occupational UV exposure tied to two-fold increase in skin cancer risk
Most physicians on Twitter with a financial conflict of interest and frequent tweets mention specific drugs for which they have a conflict

Physicians Tweeting About Drugs May Have Conflict of Interest

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Physicians with financial conflict of interest often mention specific drugs for which they have a conflict
For women with diabetes

Caffeine Tied to Lower Mortality in Women With Diabetes

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Women who consumed caffeine from coffee had reduced risk of all-cause, cardiovascular deaths