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There is an increased risk of developing cardiovascular disease among patients with idiopathic thrombocytopenic purpura

Idiopathic Thrombocytopenic Purpura Tied to Higher CVD Risk

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Risk further increased among patients with ITP who undergo splenectomy
Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program

For Hospitals, No Benefit for Early Adoption of Financial Incentives

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Hospitals with early adoption do not have better process scores, lower mortality than late adopters
In both men and women in the United States

Cancer Death Rate Continuing to Decline in United States

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Continuous drop in combined cancer death rate from 1991 to 2015, resulting in 2,378,600 fewer deaths
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

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Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans
Breast implants are associated with an increased risk of anaplastic large-cell lymphoma in the breast

Breast Implants Slightly Increase Risk of Breast ALCL

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Implants tied to increased risk of anaplastic large-cell lymphoma; overall risk still very small
Although patients with pre-existing autoimmune disease who receive checkpoint inhibitors (CPIs) are at risk for exacerbation of their disease

Immune-Related Adverse Events Up With Checkpoint Inhibitors

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Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy
Few modern

Few Immuno-Oncology Agents Reach ASCO Efficacy Thresholds

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Durable survival, response rates rarely recognized as significant by current oncology value frameworks
Hematopoietic stem/progenitor cell-derived chimeric antigen receptor T-cells are capable of long-term engraftment in a model of HIV/AIDS

HSPC-Derived CAR T-Cells Capable of Lasting Engraftment

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Chimeric antigen receptor T-cells persisted more than 2 years without measurable toxicity in primate model

December 2017 Briefing – Hematology & Oncology

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Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for December 2017. This roundup includes...
A same-day

Same-Day, Low-Dose Bowel Prep Feasible for Colonoscopy

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For inpatients at high risk of poor bowel prep, same-day 1-liter polyethylene glycol-based prep effective