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The first biosimilar drug to Neulasta has been approved by the U.S. Food and Drug Administration. Fulphila (pegfilgrastim) is approved for patients with non-myeloid cancer who are receiving myelosuppressive chemotherapy and have symptoms of febrile neutropenia.

FDA OKs 1st Biosimilar to Prevent Chemo-Related Infections

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Fulphila, biosimilar to Neulasta, helps reduce risk of infection during cancer treatment
A considerable proportion of breast cancer survivors do not undergo annual surveillance breast imaging

Many Breast Cancer Survivors Do Not Undergo Annual Surveillance

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In year 1, 13 percent did not undergo MRI or mammography; up to 19 percent by year 5
For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer

ASCO: Pembrolizumab Superior for Initial Tx of Advanced NSCLC

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Improved overall survival versus chemotherapy regardless of the PD-L1 tumor proportion score
Costs of treatment for metastatic colorectal cancer are significantly higher in Western Washington State than in British Columbia

ASCO: mCRC Costs Up in Western Washington vs. British Columbia

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No significant difference between regions in median OS for those receiving, not receiving systemic tx
A highly personalized therapy targeting multiple tumor antigens shows promise for metastatic breast cancer

Personalized Therapy Promising in Metastatic Breast Cancer

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Adaptive transfer of mutant-protein-specific tumor-infiltrating lymphocytes leads to disease regression
For patients with metastatic renal cell carcinoma classified as having intermediate or poor prognostic risk

ASCO: Sunitinib Alone Noninferior in Metastatic Renal Cell Cancer

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Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival
For women with hormone-receptor-positive

ASCO: Endocrine Tx Noninferior for HR+, HER2− Breast Cancer

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Similar efficacy for endocrine, chemoendocrine tx for women with midrange 21-gene recurrence score
The oxaliplatin

ASCO: mFOLFIRINOX Improves Survival in Pancreatic Cancer

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And, pre-op chemoradiotherapy linked to longer overall survival than immediate surgery

May 2018 Briefing – Hematology & Oncology

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Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for May 2018. This roundup includes...
Male thyroid cancer survivors have a nearly 50 percent higher risk of developing cardiovascular disease than female survivors within five years of cancer diagnosis

Male Thyroid Cancer Survivors Face Higher CVD Risk

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Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk