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Female Sex, Work Culture Biggest Contributors to Physician Burnout

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Compared with electronic health record usage at an academic medical center, clinician sex and work culture contributed more to burnout

Steroids Unrelated to Psychological Reactions in Pediatric ALL

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Low-quality evidence suggests type/dose of steroid not linked to adverse psychological reactions, possibly associated with sleep problems

FDA Moves to Resume Use of J&J COVID Vaccine

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Johnson & Johnson has agreed with the U.S. Food and Drug Administration to add a warning label to the vaccine

FDA Approves Immunotherapy for dMMR Endometrial Cancer

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Jemperli approved for dMMR endometrial cancer that progressed after platinum-containing chemotherapy treatment

Sacituzumab Govitecan Treats Metastatic Triple-Negative Breast Cancer

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Progression-free, overall survival prolonged with sacitizumab govitecan versus single-agent chemotherapy

Survivors of Adolescent, Young Adult Cancer Face Financial Hardships

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Hardships include forgoing care and medication nonadherence due to cost

Margin-Positive Surgery Still Beneficial in Pancreatic Cancer

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Survival benefit seen for surgery, even with R1/R2 resection margins compared with chemotherapy alone for stage II pancreatic cancer

Mechanism ID’d for Thrombosis After ChAdOx1 nCoV-19 Vaccine

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Testing for antibodies to platelet factor 4 positive in 22 of 23 patients; treatment with platelet transfusion should be avoided

Surgical Technique May Cut Positive Margin Rates in DCIS

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Cavity shave margin resections for pure ductal carcinoma in situ may lower risk for positive margins