Guidelines Updated for Barrett Esophagus Diagnosis, Management
Guideline revised to synthesize current best practices in the management of Barrett esophagus
Mitapivat Superior to Placebo for Pyruvate Kinase Deficiency
Early, sustained, clinically significant hemoglobin response seen in 40 percent of patients receiving mitapivat versus none in the placebo group
Sharp Spike Seen in Air Pollution Levels in Recent Years
A climate change-driven increase in wildfires may be one of the reasons for the worsening air pollution nationwide
AACR: Novel COVID-19 Vaccine Aimed at Immunocompromised Patients
CoVac-1, a peptide vaccine, induces T-cell immune responses in those with B-cell deficiencies, particularly leukemia and lymphoma patients
Ivosidenib + Azacitidine Ups Event-Free Survival in IDH1-Mutated AML
Event-free survival significantly longer compared with placebo and azacitidine for newly diagnosed IDH1-mutated AML
Non-O Blood Type Time-Dependent Predictor of VTE in Cancer
In patients with intermediate or low thrombotic risk tumor types, non-O blood type linked to increased VTE risk
Medical Financial Hardship Tied to Higher Mortality in Cancer Survivors
Health insurance coverage played critical role in this association for adults aged 64 years and younger
Many Medicare Beneficiaries Do Not Fill High-Price Prescriptions
Among beneficiaries without low-income subsidy, noninitiation reported in 30 percent of those with new prescriptions for anticancer drugs
Role of Molecular Factors in BMI, Endometrial Cancer Link Studied
Evidence of mediating role seen for fasting insulin, bioavailable testosterone, and sex-hormone binding globulin
Use of Extrapolation Common in FDA New Drug Approvals
Extrapolation of the findings from pivotal clinical trials to the approved indication most common for disease severity