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Up to two-thirds of Alzheimer's cases worldwide may stem from any of nine conditions that often result from lifestyle choices

Nine Modifiable Factors May Be Key in Reducing Alzheimer’s Risk

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Evidence suggests benefit from addressing related potentially modifiable risk factors
Two-thirds of acute abdominal aortic aneurysm events occur in those aged ≥75 years

Two-Thirds of Acute AAA Occur in Those Aged 75 Years and Older

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Overall, 96.4 percent of events in men aged younger than 75 years occur in ever smokers
There is considerable variation in the unit cost of topical corticosteroids across potencies and by branded generic or generic product

Considerable Variation in Cost of Generic Topical Corticosteroids

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Variation in cost seen across potencies, class, and by branded generic or generic product
Strategies can be adopted for improving physician resilience and the ability to handle the challenges presented by patient care

Report Highlights Ways to Improve Physician Resilience

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Recommendations include keeping a gratitude journal, enlisting peer support, learning new things
Use of patient navigators as inpatient care facilitators shortens hospital length of stay

Patient Navigators Tied to Shorter Hospital Stays

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Use of patient navigators on general medical service didn't affect readmissions
Evening and morning cortisol levels in older people may be differentially associated with tissue volume in gray and white matter structures and cognitive function

AM, PM Cortisol Tied to Brain, Cognitive Variances in Later Life

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Higher evening salivary cortisol levels tied to lower brain volume, worse cognitive function
Trials should be conducted to better establish the cardiovascular safety of testosterone therapy

Heart Safety of Testosterone Unclear for Older Men

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Most men prescribed testosterone have age-related hypogonadism, for which treatment is not approved
A single nucleotide variant in the FTO obesity locus disrupts a conserved motif

Role of SNP Variant in FTO Explored in Obesity

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Study identifies mechanistic basis for the strongest genetic association with obesity
Lumbar spine bone mineral density increases fracture risk among women with lower lumbar spine T-score than femoral neck T-score

Lumbar Spine BMD Ups Fx Risk in Women With Discordant T-Scores

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Lower T-score for lumbar spine than femoral neck increases fracture risk, particularly in older women
The U.S. Preventive Services Task Force (USPSTF) has found no net benefit for chronic obstructive pulmonary disease screening in asymptomatic adults and consequently recommends against screening. These findings form the basis of a draft recommendation statement published online Aug. 17 by the USPSTF.

USPSTF Draft Recommendation Urges Against COPD Screening

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Grade D statement recommends against routine screening for asymptomatic adults