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10 Percent of New Drugs Approved Without Meeting Primary Efficacy End Points

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Findings seen for 21 drug approvals between 2018 and 2021, with only one-third needing postmarketing studies

Incidence of Pancreatic Cancer Increasing in Younger Women

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Difference in average annual percentage change due to increasing incidence in Blacks, adenocarcinoma histopathological subtype, tumor location

Practicing Physicians Saw Excess Mortality During COVID-19 Pandemic

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However, physicians had substantially lower excess mortality than the general U.S. population

ChatGPT Scores Close to Passing U.S. Medical Licensing Exams

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ChatGPT performs at or near the passing threshold of 60 percent accuracy without specialized training

Exercise in Middle-Age Not Linked to Pelvic Floor Disorders

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However, likelihood of urge urinary incontinence increased with early adulthood history of competitive sports

Could a Vibrating Pill Ease Chronic Constipation?

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Recently FDA-approved pill, Vibrant, stimulates the colon, causing muscle contractions that move food out

Rhinoviruses, Enteroviruses Persisted During Pandemic Among Pediatric Patients

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From October 2020 to February 2021, rhinoviruses and/or enteroviruses detected at same or higher odds than in prepandemic months

Hospital Volume Affects Liver Surgery Outcomes

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Rates of in-hospital mortality, failure to rescue decreased from a hospital volume threshold of >25 liver resections per year

Defensive Information Processing Is Barrier to CRC Screening Uptake

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Odds of FIT-based screening lower with suppression subdomains of 'deny immediacy to be tested' and 'self-exemption'

More Than 400 Snacks, Sandwiches Recalled Over Listeria Concerns

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Products recalled after environmental samples tested positive for L. monocytogenes; no reports of illness so far