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The bacterial cell wall-derived muramyl dipeptide postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice

Postbiotic Could Lower Glucose, Inflammation in Obesity

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MDP postbiotic linked to reduction in hepatic insulin resistance during obesity, low-level endotoxemia
A fatal case of propofol-induced acute necrotizing pancreatitis has been described in a case report published online April 10 in the Journal of Clinical Pharmacy and Therapeutics.

Fatal Case of Suspected Propofol-Induced Pancreatitis Described

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57-year-old woman developed severe abdominal pain with nausea, vomiting after thyroidectomy
Consuming excess choline raises levels of the bacteria-produced compound trimethylamine N-oxide and increases the tendency of platelets to clump together and form clots

Gut Bacteria May Convert Choline Into Clot-Enhancing Compound

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Significant increase in plasma TMAO levels at one and two months; increase attenuated by aspirin
Hepatitis B virus reactivation is a safety concern for patients with HBV and hepatitis C virus coinfection receiving direct-acting antiviral agents

HBV Reactivation Is Concern With DAA Tx in HBV-HCV Coinfection

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29 cases of HBV reactivation reported in patients with coinfection receiving direct-acting antivirals
Follow-up colonoscopy after 10 months is associated with an increased risk of colorectal cancer and advanced-stage disease among patients with a positive fecal immunochemical test result

Waiting 10 Months for Colonoscopy May Raise CRC Risk

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After positive FIT result, colonoscopy at 10 months also tied to more advanced disease
The benefits of sharing notes with patients include improved patient engagement and empowerment

Potential Benefits, Risks of OpenNotes Discussed

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Benefits include improved patient engagement, while risks include avoidance of writing candidly
Bariatric surgery is associated with an increased risk of abdominal surgery during subsequent pregnancy

Pre-Pregnancy Bariatric Surgery Ups Risk of Abdominal Surgery

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Findings among women in first pregnancy after bariatric surgery
Guidelines relating to the appropriate adjuvant regimen for patients with pancreatic cancer have been updated in light of new evidence

ASCO Updates Recs on Potentially Curable Pancreatic Cancer

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Regimen of gemcitabine, capecitabine preferred in absence of concerns for toxicity, tolerance
Young doctors often have unprofessional or offensive content on their Facebook profiles

Doctors Need to Be Mindful of What They Post on Social Media

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Investigators find many examples of unprofessional, 'potentially objectionable' behavior online
Fewer Americans with Crohn's disease are being hospitalized than in the past

CDC: Hospitalization Rates Stabilizing for Crohn’s Disease

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Improvement from 1998 to 2004 which saw more than 4 percent increases in hospitalizations each year