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General and central obesity are associated with breast cancer risk

General, Central Obesity Linked to Specific Breast Cancer Risk

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General obesity, indicated by BMI, more strongly linked to ER+/PR+ subtype
For patients with noncancer pain and opioid-induced constipation

Naloxegol Has No Effect on Opioid Dose in Opioid-Tied Constipation

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Centrally-mediated analgesia was maintained during treatment with naloxegol in noncancer pain, OIC
For hepatitis B virus carriers

HBcrAg Levels Tied to Progression to Cirrhosis in HBV Carriers

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After adjustment, hepatitis B virus core-related antigen was independently linked to progression
Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets

Insurer Market Power Lowers Providers’ Prices

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Evidence seen for specialists in markets with high provider, insurer concentration
For patients with severe obesity

Long-Term Weight Loss, T2DM Remission for Roux-en-Y Surgery

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Twelve-year follow-up shows durability of weight loss and remission and prevention of type 2 diabetes
Administration of histamine-producing gut microbes to histidine decarboxylase-deficient mice reduces inflammation and tumor formation

Histamine May Play Role in Colorectal Tumorigenesis

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Histamine-producing probiotic reduces inflammation, suppresses colon tumors in mice
For patients undergoing liver surgery

Extended Thromboprophylaxis Safe, Effective After Liver Surgery

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Severe complication rate 5.6 percent, with no 90-day mortalities
Monthly feedback significantly improves colonoscopy quality measures

Monthly Feedback Linked to Improved Colonoscopy Quality

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But no improvement observed with quarterly feedback
The American College of Physicians does not support the legalization of physician-assisted suicide

ACP Does Not Support Legalization of Assisted Suicide

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Legalization would affect trust in the patient-physician relationship, and in the medical profession
Programmed death-ligand 1 is primarily expressed in metastatic colorectal cancer lesions

PD-L1 Mainly Expressed in Metastatic CRC Lesions

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Overall, 81.8 percent of metastatic CRCs and 40.9 percent of primary lesions had PD-L1 expression