Model Can Predict, Stratify Liver Cancer Risk in Noncirrhotic Chronic Hep B
New model exhibited satisfactory discrimination and calibration, with c-statistics of 0.844 and 0.813 in derivation, validation cohorts
GLP-1 RA Use Linked to Reduced Cirrhosis Risk in MASLD, Diabetes
Compared with DPP-4i use, GLP-1 RA use also associated with lower risk for composite of cirrhosis complications, mortality
FDA Approves Tremfya for Ulcerative Colitis
Approval is for adults with moderately to severely active disease
Recommendations Issued for Managing Chronic Constipation
Six strong recommendations developed, including initial management of dietary modifications and ensuring adequate fluid, fiber intake
Long-Course Chemoradiotherapy Preferred TNT Regimen for Rectal Cancer
LCCRT results in higher two-year organ preservation and lower two-year local regrowth compared with short-course radiotherapy
Upper GI Mucosal Damage Tied to Later Parkinson Disease Diagnosis
Authors say increased vigilance is warranted for patients with mucosal damage
Omitting 5-FU Bolus Does Not Reduce Survival in Advanced Cancer
However, omission does result in reductions in neutropenia, thrombocytopenia, and use of granulocyte colony-stimulating factor
Palliative Low-Dose Radiotherapy Improves Pain in Hepatic Cancer
Improvement in hepatic pain seen in 67 percent of patients receiving radiotherapy plus best supportive care
Most Patients With Stage I PDAC Are Upstaged on Histopathology
More than 70 percent with stage I pancreatic ductal adenocarcinoma and about 30 percent with stage II PDAC upstaged after surgery
Women With Liver Cancer Less Likely Than Men to Receive Liver Transplant
Furthermore, women are more likely to die waiting for a donor liver than men