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Model Can Predict, Stratify Liver Cancer Risk in Noncirrhotic Chronic Hep B

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New model exhibited satisfactory discrimination and calibration, with c-statistics of 0.844 and 0.813 in derivation, validation cohorts

GLP-1 RA Use Linked to Reduced Cirrhosis Risk in MASLD, Diabetes

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Compared with DPP-4i use, GLP-1 RA use also associated with lower risk for composite of cirrhosis complications, mortality

FDA Approves Tremfya for Ulcerative Colitis

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Approval is for adults with moderately to severely active disease

Recommendations Issued for Managing Chronic Constipation

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Six strong recommendations developed, including initial management of dietary modifications and ensuring adequate fluid, fiber intake

Long-Course Chemoradiotherapy Preferred TNT Regimen for Rectal Cancer

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LCCRT results in higher two-year organ preservation and lower two-year local regrowth compared with short-course radiotherapy

Upper GI Mucosal Damage Tied to Later Parkinson Disease Diagnosis

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Authors say increased vigilance is warranted for patients with mucosal damage

Omitting 5-FU Bolus Does Not Reduce Survival in Advanced Cancer

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However, omission does result in reductions in neutropenia, thrombocytopenia, and use of granulocyte colony-stimulating factor

Palliative Low-Dose Radiotherapy Improves Pain in Hepatic Cancer

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Improvement in hepatic pain seen in 67 percent of patients receiving radiotherapy plus best supportive care

Most Patients With Stage I PDAC Are Upstaged on Histopathology

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More than 70 percent with stage I pancreatic ductal adenocarcinoma and about 30 percent with stage II PDAC upstaged after surgery

Women With Liver Cancer Less Likely Than Men to Receive Liver Transplant

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Furthermore, women are more likely to die waiting for a donor liver than men