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Specific patterns of opioid administration to opioid-naive inpatients are associated with risk for long-term use after discharge

Patterns of Inpatient Opioid Use Linked to Long-Term Use

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Outpatient use at 90 days was seen for 5.9 and 3.0 percent of patients with and without inpatient use
Use of pantoprazole for up to three years to prevent upper gastrointestinal events in patients receiving anticoagulant therapy with aspirin and/or rivaroxaban has a similar safety profile to placebo except for an increased risk for enteric infections

PPI Use for Up to Three Years Safe During Anticoagulant Tx

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Safety profile did not differ for pantoprazole versus placebo except greater risk for enteric infections
Three large drug makers have launched a legal challenge against the Trump administration's rule requiring the prices of drugs to be included in television ads.

Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

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Lawsuit against the rule filed Friday by Merck, Eli Lilly, and Amgen
Drug- and alcohol-related mortality is significantly higher than expected in the seven years following bariatric surgery

Drug- and Alcohol-Related Deaths Higher After Bariatric Surgery

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Standardized mortality rates from substance use higher after Roux-en-Y gastric bypass
Marketplace introduction of infliximab has not resulted in reductions in the population rates of inflammatory bowel disease-related hospitalizations or intestinal resections or colectomies

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations

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Introduction of infliximab did not lead to drop in hospitalization, intestinal resection, colectomy
On Thursday

FDA Warns of Infections From Fecal Transplants After One Death

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Fecal microbiota transplantation is a still-experimental procedure, as yet unapproved by the FDA
Reflux symptoms return in about half of patients who undergo gastric bypass

Weight Loss Surgery May Not Relieve Acid Reflux

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Symptoms return in half of patients undergoing long-term follow-up after gastric bypass
Nitrate pollution of drinking water has serious health and economic consequences

Nitrate Pollution of Tap Water May Cause Thousands of Cancer Cases

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Annual nitrate-attributable cases of CRC, ovarian, thyroid, kidney, bladder cancer ranged from 2,300 to 12,594
Many health care providers in the United Kingdom have little direct experience with online feedback

Most Providers Unaware of Online Feedback About Themselves

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Providers do not encourage patient reviews and often view such feedback as having limited value
The incremental diagnostic yield of Lynch syndrome screening decreases substantially after age 70 to 75 years

Diagnostic Yield of Lynch Syndrome Screening Drops With Age

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Incremental diagnostic yield decreases substantially after 70 to 75 years; LS is rare after 80 years