Gastroenterology

Device provides minimally invasive way to resect and remove necrotic tissue in patients with walled-off pancreatic necrosis

Young-onset esophageal adenocarcinoma presenting at more advanced stages; proportion of advanced stage up from 1975 to 2015

Irinotecan, cetuximab, and vemurafenib improve progression-free survival in BRAF^V600E-mutated colorectal cancer

However, outcomes are not always better than those of average citizens in 12 comparison countries

And age-adjusted rate of drug overdose deaths increased from 20.7 to 21.6 per 100,000 from 2018 to 2019

Authors suggest use of positive diagnostic strategy for improving time to initiation of appropriate therapy

Adenocarcinomas increasing in most early-onset subgroups; carcinoid tumors increasing more steeply in all age groups

Findings strongest for autoimmune diseases involving the skin, the gastrointestinal tract, or connective tissue

Authors say these findings suggest no need for intensive surveillance after three years

Overall, only 2 percent of infants tested were positive for COVID-19, but one-third required hospitalization