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Microneedle array delivery of trimeric coronavirus spike protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 infection

Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

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Microneedle array-delivered S1 subunit vaccine elicits potent antigen-specific antibody response in mice
Here are what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3

Physician’s Briefing Weekly Coronavirus Roundup

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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
Real-world data support the benefit of using the Medtronic MiniMed 670G insulin pump system for glycemic control in type 1 diabetes

ENDO: Real-World Data Analyzed for Use of Insulin Pump in T1DM

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Subgroup analysis shows time spent in target glucose range increased in auto mode versus manual mode
Following implementation of the Affordable Care Act

Unemployed Workers Less Likely to Be Uninsured Post-ACA

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Following implementation of ACA, insurance rates decreased more in states with Medicaid expansion
Disruptions in insurance coverage around the time of pregnancy disproportionately affect indigenous

Racial Disparities Seen for Insurance Coverage Around Time of Pregnancy

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Spanish-speaking Hispanic women had the lowest rates of steady insurance
Certain patient and presentation factors increase the likelihood of a missed appendicitis diagnosis in the emergency department

Risk Factors for Missed Appendicitis Diagnosis Identified

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6 percent of adults and 4.4 percent of children misdiagnosed during initial emergency department visit
Proton pump inhibitors taken for acid reflux may lead to an increased risk for fractures in children and adolescents

Proton Pump Inhibitor Therapy May Up Fracture Risk in Children

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Fracture risk remained higher after adjusting for differences in sex, race, other factors
Endoscopy within six hours versus six to 24 hours after consultation is not associated with lower 30-day mortality in patients with acute upper gastrointestinal bleeding who are at high risk for further bleeding or death

Endoscopy Within Six Hours Does Not Lower Mortality in GI Bleed

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30-day mortality did not differ for those undergoing endoscopy within six hours versus six to 24 hours
From 2011 to 2017

Burden of Clostridioides difficile Infection Down in the U.S.

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Decrease seen in adjusted estimate of national burden of health care-associated C. difficile infection
Most macronutrient diets result in modest weight loss and improvements in cardiovascular risk factors over six months

Weight Loss Modest for Most Macronutrient Diets

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Weight loss, CV risk factors improved over six months, but benefits mainly diminished at 12 months