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Medicare paid at least $1.5 billion over a decade to replace seven types of defective heart devices that apparently failed for thousands of patients

Medicare Paid $1.5 Billion to Replace Faulty Heart Devices

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Reasons for replacement included recalls, premature failures, medically necessary upgrades, infections
For patients at high risk for breast cancer

Provider Advice Impacts Breast Cancer Prevention Decisions

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Worry, trust also affect choice on whether to use selective estrogen receptor modulators
For patients undergoing total hip arthroplasty

Patient Factors Differ for Surgical, All-Cause Readmission

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Highest odds of return to theater after hip surgery tied to drug abuse, psychoses, dementia, depression
A stepped care case-finding intervention is beneficial for individuals with post-traumatic stress disorder after a natural disaster

Stepped Care Intervention Beneficial After Natural Disaster

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Has greater reach, is superior for reducing prevalence of PTSD, with benefit at 6 months
Patients diagnosed with melanoma are more likely to have treatment delays if they are nonwhite or on Medicaid

Insurance Type Linked to Surgery Delay in Melanoma

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Surgical treatment delays increased for Medicaid versus private patients, for nonwhite patients
General practitioners are less likely to support cessation of smoking in patients with cancer than in those with coronary heart disease

Smoking Cessation Support Less Likely for Cancer Patients

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General practitioners less likely to support smoking cessation in patients with cancer than with CHD
For patients with acute heart failure admitted to the emergency department

ER Risk Score Predicts 30-Day Mortality in Acute Heart Failure

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Risk score based on 13 independent risk factors has excellent discrimination and calibration
Immediate or delayed differences in adverse event rates were seen after generic commercialization of three antihypertensive drugs

Commercialization of Generics Impacts Adverse Event Rates

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Adverse events up for generic users of losartan, valsartan, candesartan in month of commercialization
Many basic scientists and clinical researchers support somatic genome editing in adults for prevention of serious disease but not for human enhancement; they also believe the public should be consulted before any clinical application of germline gene editing proceeds

Scientists Support Genome Editing to Prevent Disease

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Majority of survey respondents support gene editing to treat diseases but not human enhancement
Treatment with long-acting muscarinic antagonists plus long-acting β-agonists is associated with fewer exacerbation events in patients with chronic obstructive pulmonary disease

LAMA Plus LABA Tied to Fewer Exacerbations in Stable COPD

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Also might result in greater improvement in FEV1 than LABA plus corticosteroids