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The U.S. Preventive Services Task Force has concluded that the current evidence is insufficient to assess the balance of benefits and harms of screening for adolescent idiopathic scoliosis in children and adolescents aged 10 to 18 years. The recommendation statement has been published in the Jan. 9 issue of the Journal of the American Medical Association.

USPSTF Questions Adolescent Idiopathic Scoliosis Screening

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Finds insufficient evidence on balance of benefits and harms of screening asymptomatic 10- to 18-year-olds
The use of idalopirdine does not improve cognition versus placebo over 24 weeks of treatment for patients with mild-to-moderate Alzheimer's disease

Idalopirdine May Not Improve Cognition in Mild Alzheimer’s

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Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks
A novel oral dosage form enables sustained release of antiretrovirals

Week’s Worth of HIV Meds in a Single-Dose Capsule Feasible

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Oral platform delivers three antiretrovirals for up to seven days after single administration
Pediatric sports- and recreation-related eye injuries are common

Pediatric Sports-, Recreation-Related Eye Injuries Common

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About half of hospitalizations during period studied from non-powder gun-related injuries, mostly in boys
For patients with type 2 diabetes

Increased Long-Term Mortality for All Weight Categories in T2DM

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Nadir at BMI of 25 to <30 kg/m²; stepwise increase to peak for patients with BMI ≥40 kg/m²
For high school students

2005 to 2015 Saw Fewer High School Students Having Sex

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Significant drop in proportion of high school students who had ever had sexual intercourse nationwide
Vaccination for influenza for multiple seasons is twice as effective in preventing severe influenza -- compared with non-severe influenza -- in older patients admitted to hospital

Repeated Flu Vaccinations Help Prevent Severe Infection

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Annual vaccination found to lessen flu severity, hospitalizations, and death among the elderly
There is an increased risk of developing cardiovascular disease among patients with idiopathic thrombocytopenic purpura

Idiopathic Thrombocytopenic Purpura Tied to Higher CVD Risk

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Risk further increased among patients with ITP who undergo splenectomy
Two years of high-intensity exercise training is associated with improved maximal oxygen uptake and reduced cardiac stiffness in previously sedentary healthy middle-aged adults

CV Exercise Betters Cardiac Aging in Sedentary Middle-Aged Adults

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Two years of high-intensity exercise tied to improved maximal oxygen uptake, reduced cardiac stiffness
The new adjuvanted herpes zoster subunit vaccine is cost-effective compared with the currently recommended live attenuated herpes zoster vaccine

Adjuvanted Shingles Subunit Vaccine Likely More Cost-Effective

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Less overall cost and more effective than live attenuated vaccine at all ages; generally a good value