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Transdermal estradiol plus intermittent micronized progesterone can prevent clinically significant depressive symptoms among euthymic perimenopausal and early postmenopausal women

Transdermal Estradiol May Help Prevent Depressive Symptoms

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Effects of TE, micronized progesterone seen in perimenopausal, early postmenopausal women
For community-dwelling older adults

Adherence to Mediterranean Diet Linked to Reduced Frailty

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Lower risk of incident frailty for community-dwelling older adults with greater adherence to the diet
Children with psoriasis have an increased risk of comorbidities compared to children without psoriasis

Psoriasis Is Independent Risk Factor for Comorbidity in Children

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Those with psoriasis at higher risk for diabetes, liver disease, elevated lipid levels independent of obesity
For young adults without known risk factors

HIV Screening Most Optimal at 25 Years of Age If No Risk Factors

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Simulation favors screening at 25 for adolescents, young adults without identifiable HIV risk factors
A long-term physical activity program is not associated with reduced risk of frailty among community-dwelling older adults with functional limitations

Physical Activity Doesn’t Seem to Reduce Risk of Frailty in Elderly

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Baseline frailty didn't modify effect of physical activity on reducing major mobility disability
Children with a physical condition frequently have a mental disorder

Mental Disorders Common in Kids With Chronic Physical Conditions

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Baseline multimorbidity tied to decreases in physical, psychological, and school environment quality of life
Higher-intensity end-of-life care may be driven by financial incentives present in fee-for-service Medicare but not in the Veteran Affairs integrated system

Intense End-of-Life Care Found to Be Less Likely for VA Patients

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Authors say results have important implications for the future of VA care, Medicare policy
Assessing change in the CHA2DS2-VASc score over time is more predictive of ischemic stroke in patients with atrial fibrillation than the baseline score

Follow-Up Delta CHA2DS2-VASc Score Better Predicts CVA in A-Fib

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CHA2DS2-VASc score not static; most a-fib patients develop new risk factor before ischemic stroke
There have been recent modest declines in severe obesity among young children

Recent Modest Declines Noted in Severe Obesity in Children

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In children aged 2 to 4, prevalence rose from 2000 to 2004, then fell from 2004 to 2010 and 2010 to 2014
There is urban and rural variation in fertility-related behavior among U.S. women

Urban, Rural Variation in Fertility-Related Behaviors for U.S. Women

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Younger average age at first intercourse in rural areas; more women in rural areas had ≥1 birth