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Disrupted sleep is associated with increased amyloid-β production in adults

Disrupted Sleep Linked to Increased Amyloid-β Production

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Sleep deprivation tied to increased overnight amyloid-β-38, -40, -42 levels by 25 to 30 percent
Among commercially-insured patients

Observation Care Cost Saving in Commercially-Insured Patients

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Total, out-of-pocket spending considerably lower for observation care; both increased from '09 to '13
For postoperative patients there is considerable variation in the amount of opioids prescribed at hospital discharge

Amount of Opioids Prescribed After Hospital Discharge Varies

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45.6 percent of patients using no opioids 24 hours predischarge were prescribed opioids at discharge
Allopurinol prescribing is more likely if patients meet eligibility criteria at diagnosis

Allopurinol Rx More Likely With Eligibility at Diagnosis

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More frequent chronic disease reviews needed to assess eligibility for allopurinol
The five-month Community Aging in Place

CAPABLE Program Saves Money for Seniors With Disability

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Largest differential reduction in expenditures seen for inpatient care, long-term services, supports
The absence of standards is an important barrier to pediatric oncologists recommending medical marijuana

Pediatric Oncologists Willing to Consider Medical Marijuana

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Those eligible to certify report less favorable attitudes to medical marijuana overall
Omalizumab improves the efficacy of multifood oral immunotherapy among pediatric patients with multifood allergies

Omalizumab Ups Efficacy of Multifood Oral Immunotherapy

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Findings in multifood allergic pediatric patients
The U.S. Preventive Services Task Force recommends against use of hormone therapy for preventing chronic conditions in postmenopausal women. These findings form the basis of a final recommendation statement published in the Dec. 12 issue of the Journal of the American Medical Association.

USPSTF Recommends Against Hormone Tx Post Menopause

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Benefits do not outweigh harms of using hormone therapy for prevention of chronic conditions
A deep learning algorithm can detect metastases in sections of lymph nodes from women with breast cancer; and a deep learning system has high sensitivity and specificity for identifying diabetic retinopathy

Artificial Intelligence Promising for CA, Retinopathy Diagnoses

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Two studies evaluate use; one for breast cancer, the other for diabetic retinopathy
In-hospital mortality among patients with atrial fibrillation is higher in rural hospitals than in urban hospitals

In-Hospital Deaths in A-Fib Patients Higher in Rural Areas

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Risk of death is 17 percent higher in rural versus urban hospitals