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A toll-like receptor 9 agonist in the presence of alum is stable over a month and elicits strong anti-heroin antibody titers and blockade of heroin-induced antinociception

Anti-Heroin Vaccine Shows Promise Against Lethal Doses

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TLR9 agonist in presence of alum is stable over 30 days, elicits strong anti-heroin antibody titers
Rotating shift work which includes night shifts is associated with increased odds of type 2 diabetes

Rotating Night Shift Work Tied to Increased Odds of T2DM

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Working more night shifts per month linked to increased odds of type 2 diabetes
The developmental-behavioral pediatric workforce struggles to meet current service demands

Significant Challenges for Developmental-Behavioral Peds

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Care issues include long waits, high case complexity, poor reimbursement, and provider burnout
As part of the Choosing Wisely campaign

AAP, POSNA Release 5 Pediatric Orthopedic Recommendations

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Five tests/procedures often inappropriately ordered highlighted as part of Choosing Wisely campaign
The first blood test designed to help health care professionals evaluate mild traumatic brain injury has been approved by the U.S. Food and Drug Administration.

FDA Approves First Blood Test to Evaluate Potential Concussions

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Should help reduce unnecessary CT testing and associated radiation exposure
For low risk patients with suspected pulmonary embolism

Safety of PERC Tool Validated for Very Low Risk PE Rule Out in ER

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Eight-item, pulmonary embolism rule-out criteria safe for use with very low risk patients in ER
Very low-dose 222-nm UVC ultraviolet light can inactivate more than 95 percent of aerosolized H1N1 influenza virus

Low Dose-Rate Far-UVC Light Can Inactivate Influenza Virus

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Far-UVC at 222-nm light can inactivate aerosolized viruses; >95 percent of H1N1 influenza inactivated
From 1984 to 2012

Kidney Stone Incidence Increased Between 1984 and 2012

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The increase included both symptomatic and asymptomatic kidney stones
For hospitalized patients with heart failure with preserved ejection fraction

Poor Outcomes With Systolic BP Below 120 mm Hg in HFpEF

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Increased risk of heart failure readmission at 30 days; of mortality, combined end point at 30 days, one year
For patients undergoing imaging examinations

Education About Imaging Most Often Given by Ordering Provider

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Delivery of pre-examination information to patients suboptimal; about half seek information themselves