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Trials to evaluate drugs or devices used to treat chronic medical conditions that are published early in the chain of evidence often show an exaggerated treatment effect compared with subsequent trials

Early Studies Often Show Exaggerated Treatment Effect

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Findings based on assessment of trials evaluating drugs, devices to treat chronic medical conditions
From 2011 to 2014

RBC, Plasma Transfusions Drop From 2011 to 2014

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Red blood cell and plasma transfusions decreased, while platelet transfusions remained stable
In a position paper published online Feb. 27 in the Annals of Internal Medicine

Recommendations for Optimizing Hidden Curriculum in Medicine

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Clinical learning environment should be optimized by ensuring what is taught in classroom is modeled
Understanding nonadherence in patients and encouraging a change in attitude toward patients and their medication can improve medication adherence

Understanding Rx Nonadherence Can Improve Adherence

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Changing attitudes toward patients and their medication adherence can improve adherence
Artificial intelligence

Artificial Intelligence May Help Prevent Physician Burnout

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Many potential uses for AI, including improving searches and documentation, selecting treatment
The antibiotic clarithromycin (brand name: Biaxin) may increase the long-term risk of heart problems and death in patients with heart disease

FDA Warns of Possible Heart Risks Linked to Clarithromycin

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Agency advising doctors to consider prescribing other antibiotics to patients with coronary heart disease
The percentage of uninsured U.S. persons of all ages did not change significantly from 2016 to the first nine months of 2017

CDC: No Change in Percentage of Uninsured in U.S. From ’16 to ’17

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Increase in percentage of those aged younger than 65 years enrolled in high-deductible health plan

American Academy of Dermatology, Feb. 16-20

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The American Academy of Dermatology's 2018 Annual Meeting The annual meeting of the American Academy of Dermatology was held from Feb. 16 to...
A number of kratom-containing dietary supplements are being recalled and destroyed by the manufacturer

FDA Cracks Down on Kratom Products

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Missouri-based Divinity Products Distribution will recall and destroy kratom-containing products
For adults with sepsis

No Evidence Use of SEP-1 Bundle Ups Survival in Sepsis

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Neither the sepsis management bundle nor its interventions improve survival for adults with sepsis