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Higher rates of decidual arteriopathy and other maternal vascular malperfusion features are seen in placentas of women with severe acute respiratory syndrome coronavirus 2

Placental Injury Seen in Pregnant Women With SARS-CoV-2

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Higher rates of decidual arteriopathy, other maternal vascular malperfusion features observed
A recombinant adenovirus type-5 vectored COVID-19 vaccine is safe

Adenovirus Type-5 Vectored COVID-19 Vaccine Shows Promise

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ELISA antibodies and neutralizing antibodies increased at day 14, peaked at day 28
For patients with COVID-19 requiring hospitalization

Hydroxychloroquine Plus Macrolides No Benefit in COVID-19

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Hydroxychloroquine, chloroquine with or without macrolides linked to in-hospital mortality, arrhythmia
The World Health Organization has suspended use of the antimalarial drug hydroxychloroquine in a clinical trial of treatments of COVID-19 after a study revealed that patients taking the drug are at increased risk for death and serious heart problems.

WHO Suspends Testing of Hydroxychloroquine in COVID-19 Patients

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In light of recent findings, hydroxychloroquine arm of WHO global study paused temporarily
The U.S. Department of Health and Human Services said Thursday it would provide up to $1.2 billion to AstraZeneca to develop a potential COVID-19 vaccine from a lab in Oxford

U.S. Offers $1.2 Billion to Drug Company for COVID-19 Vaccine Research

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Deal will fund phase 3 clinical trial in the United States this summer with about 30,000 volunteers
Older age

Age, Sex, History of Diabetes Predict Intubation in COVID-19

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Only factors independently associated with time to extubation are age and body mass index
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 18 to 22

Physician’s Briefing Weekly Coronavirus Roundup

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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
A chest X-ray severity score can predict outcomes among young and middle-aged adults with COVID-19 on presentation to the emergency department

ED Chest X-Ray Score Predicts COVID-19 Outcomes in Adults <50

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CXR severity score ≥2 and obesity independent predictors of hospital admission
Children may experience acute cardiac decompensation due to a severe inflammatory state (multisystem inflammatory syndrome in children) following infection with severe acute respiratory syndrome coronavirus 2

Cardiac Decompensation Seen in Children Following COVID-19

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Cardiac decompensation occurred in conjunction with multisystem inflammatory syndrome in some children
In Northern California

Incidence of AMI Hospitalization Down During COVID-19

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Decrease seen in incidence of STEMI, NSTEMI in Northern California during COVID-19 period versus pre-COVID-19