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The U.S. Department of Health and Human Services said Thursday it would provide up to $1.2 billion to AstraZeneca to develop a potential COVID-19 vaccine from a lab in Oxford

U.S. Offers $1.2 Billion to Drug Company for COVID-19 Vaccine Research

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Deal will fund phase 3 clinical trial in the United States this summer with about 30,000 volunteers
Older age

Age, Sex, History of Diabetes Predict Intubation in COVID-19

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Only factors independently associated with time to extubation are age and body mass index
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 18 to 22

Physician’s Briefing Weekly Coronavirus Roundup

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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
A chest X-ray severity score can predict outcomes among young and middle-aged adults with COVID-19 on presentation to the emergency department

ED Chest X-Ray Score Predicts COVID-19 Outcomes in Adults <50

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CXR severity score ≥2 and obesity independent predictors of hospital admission
Children may experience acute cardiac decompensation due to a severe inflammatory state (multisystem inflammatory syndrome in children) following infection with severe acute respiratory syndrome coronavirus 2

Cardiac Decompensation Seen in Children Following COVID-19

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Cardiac decompensation occurred in conjunction with multisystem inflammatory syndrome in some children
In Northern California

Incidence of AMI Hospitalization Down During COVID-19

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Decrease seen in incidence of STEMI, NSTEMI in Northern California during COVID-19 period versus pre-COVID-19
In 2018

Deaths From Alcohol, Drugs, Suicide Topped 150,000 in 2018

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While there was a decrease in opioid overdose deaths, alcohol and suicide deaths increased
The diagnostic specificity of severe acute respiratory syndrome coronavirus 2 serologic assays varies

Clinical Performance of SARS-COV-2 Antibody Tests Varies

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Sensitivity of both Abbot and EUROIMMUN serologic assays poor during first 14 days of symptoms
Among COVID-19 patients who develop severe respiratory symptoms requiring intubation

Asthma Tied to Longer COVID-19 Intubation Time

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However, asthma not associated with higher rates of acute respiratory distress syndrome, death
Factors associated with in-hospital mortality include older age

Factors Linked to COVID-19 In-Hospital Mortality ID’d in NYC

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22 percent of patients critically ill; older age, chronic cardiac disease linked to higher in-hospital mortality