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Diabetes Remission Increased With Dapagliflozin Plus Calorie Restriction

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Dapagliflozin plus calorie restriction beneficial for patients with overweight or obesity and type 2 diabetes

Considerable Uncertainty Exists Regarding Effects of Puberty Blockers

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Two systematic reviews revealed very low-certainty evidence on outcomes for people with gender dysphoria

Calorie Labeling of Foods Leads to Small Reduction in Energy Selected

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Larger reduction seen in consumption; evidence insufficient to assess potential modifiers for food consumption

Continuous Glucose Monitoring Can Predict Microvascular Complications in Type 1 Diabetes

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Time-in-range computed from virtual CGM data predicts retinopathy, neuropathy similarly to glycated hemoglobin data

Intermittent Fasting Safe, Effective for Reducing Visceral Adipose Tissue

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However, it offers no additional benefit than the Mediterranean diet alone for abdominal fat

No Link Seen Between GLP-1 Receptor Agonist Use and Thyroid Cancer

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Authors say large, multisite study should provide reassurance for short-term risk

Certain Drug Types Associated With Risk for Dementia

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Antimicrobials, vaccines, anti-inflammatories linked to reduced risk for Alzheimer disease and dementia; antipsychotics and diabetes drugs tied to higher risk

GLP-1 Receptor Agonists Tied to Risks and Benefits Beyond Weight Loss

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Reduced risks seen for neurocognitive, coagulation, cardiometabolic disorders; increased risks seen for GI, arthritic disorders

Websites Selling Compounded GLP-1 RAs Often Misinform Consumers

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Only 34 of 79 websites stated that compounded drugs were not FDA approved; 39 websites did not report adverse effects, warnings

Smoking Tied to Lower Earnings, Labor Market Participation

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Associations even stronger among those with lower educational attainment