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Patients with chronic myeloid leukemia who received a glitazone along with imatinib remained disease-free for up to nearly five years in a study published online Sept. 2 in Nature.

Addition of Glitazone to Chemo May Help Treat CML

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Combining glitazones with standard treatment improved survival in small study
Individuals with type 2 diabetes mellitus may be more prone to developing the neuropathology associated with Alzheimer's disease

Type 2 Diabetes Linked to More Alzheimer’s Neuropathology

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Effect may be driven by tau phosphorylation, researchers say
For patients with diabetic nephropathy receiving an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker

Finerenone Linked to Improved UACR in Diabetic Nephropathy

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Addition of finerenone to ACE inhibitor or ARB tied to reduction in urinary albumin-creatinine ratio
Many adolescents with chronic diseases such as asthma and juvenile arthritis have consumed alcohol or smoked marijuana in the last year

Many Teens With Chronic Illnesses Use Alcohol, Marijuana

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Four out of 10 high school students with medical conditions used one or both in past year

August 2015 Briefing – Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2015. This roundup includes...
The U.S. smoking rate continues to decline

CDC: Smoking Rate Falls to 15.2 Percent in the United States

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Higher tobacco taxes, tough messages contributing to decline
In patients with type 1 diabetes

Periodontal Disease Predicts CAC Progression in Type 1 Diabetes

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No link with coronary artery calcium progression for individuals without diabetes
Nonalbuminuric chronic kidney disease is associated with increased risk of cardiovascular disease and all-cause mortality

Nonalbuminuric CKD Ups Cardiovascular Morbidity in T1DM

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Also linked to increase in all-cause mortality, but not albuminuria or end-stage renal disease
The risk of osteonecrosis of the jaw is highest in association with intravenous bisphosphonate use

Osteonecrosis of Jaw Risk Highest for IV Bisphosphonate Use

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High risk for zoledronate, denosumab mainly in prevention of skeletal-related events
Use of dipeptidyl peptidase-4 inhibitors in type 2 diabetes is tied to severe joint pain in some patients

FDA Warns of Joint Pain Tied to DPP-4 Inhibitors

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Agency advises users with such symptoms to contact their doctor