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The adoption rate of the newest antidiabetes pharmacotherapy

Antidiabetes Prescriptions 15-Fold Higher Than Antiobesity Rx

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Mean increase of 25,259 prescriptions per month for SGLT2s versus 5,154 for new antiobesity meds
Metformin may help preserve cardiovascular health in patients with type 1 diabetes

Metformin Tied to Cardiovascular Benefits in T1DM Patients

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Cells associated with blood vessel damage reduced in patients taking metformin
For patients with new-onset diabetic ketoacidosis and severe hyperglycemia

Metformin, Sitagliptin Prolong Normoglycemia Remission in DKA

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Findings in African-American patients with new-onset diabetic ketoacidosis and severe hyperglycemia
For obese patients without diabetes

Rapid Improvement in Insulin Sensitivity With Bariatric Surgery

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Improvements in hepatic insulin sensitivity, endogenous glucose production, lipolysis
Dry-heat cooking that produces advanced glycation end products may increase the risk of type 2 diabetes

Avoiding Dry-Cooked Foods May Help Protect Against T2DM

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Researchers suggest steaming, poaching, and stewing for better health
Much of the weight lost via bariatric surgery appears to stay off for at least 10 years

Long-Term Follow-Up Shows Bariatric Patients Keep Weight Off

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10-year follow-up study finds many who had gastric bypass surgery maintained weight loss

August 2016 Briefing – Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2016. This roundup includes...
Dapagliflozin improves insulin sensitivity and increases lipid oxidation and plasma ketone concentration in patients with type 2 diabetes mellitus (T2DM)

Dapagliflozin Improves Insulin Sensitivity in Type 2 Diabetes

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Decrease in basal glucose oxidation; increases in lipid oxidation, plasma ketone concentration
For patients with non-insulin-treated type 2 diabetes

Δ9-Tetrahydrocannabivarin Beneficial in Type 2 Diabetes

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THCV significantly decreases fasting plasma glucose, improves pancreatic β-cell function
More than one-quarter of Canadian and Alaskan Inuit have the TBC1D4 mutation resulting in elevated postprandial glucose

TBC1D4 Mutation Common in North American Inuit

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TBC1D4 carriers with prediabetes, type 2 diabetes have increased risk of remaining undiagnosed