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The diagnosis and management of polycystic ovary syndrome is discussed in a case vignette published online July 6 in The New England Journal of Medicine.

Case Vignette Addresses Diagnosis, Management of PCOS

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Treatment decisions should be informed by patient priorities -- in this case hirsutism, irregular menses
Severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy

Diabetic Retinopathy Independently Tied to Depression

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Severe nonproliferative/proliferative diabetic retinopathy linked to greater depressive symptoms
The magnitude of the association between a multilocus genetic risk score for body mass index and BMI is larger for individuals born in later birth cohorts

Genetic Risk Score Impact on BMI Varies Across Birth Cohorts

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Larger magnitude of association between genetic risk score for BMI and BMI in later birth cohorts
Only about half of trials registered at ClinicalTrials.gov are listed in the largest data-sharing repository

Many Clinical Trials Are Not Listed in Data-Sharing Repository

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Fifty-three percent of randomized clinical trials were listed at Clinical Study Data Request website
Diabetes predicts diminished quality of life improvements after lumbar decompression surgery

Diabetes Impacts QOL Outcome After Lumbar Decompression

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Diabetes predicts diminished improvement in postoperative EuroQol 5-Dimensions
Americans get more than half of their daily calories from seven farm foods that are subsidized by the U.S. government

Obesity Tied to Consumption of U.S. Subsidy Crops

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Majority of calories consumed came from among seven subsidized food products
A mindful self-compassion program can reduce depression

Mindful Self-Compassion Program Beneficial in Diabetes

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Emotional and metabolic benefits with reductions in depression and glycated hemoglobin
Patients with osteogenesis imperfecta have an elevated risk of death

Elevated Risk of Death for Osteogenesis Imperfecta

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Higher risk of death from respiratory diseases, gastrointestinal diseases, and trauma

June 2016 Briefing – Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for June 2016. This roundup includes...
Lixisenatide and glulisine as add-on to basal insulin result in a reduction in glycated hemoglobin levels in patients with type 2 diabetes

Glucagon-Like Peptide-1 Receptor Agonists Beneficial As Add-On

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Reduction in HbA1c with both lixisenatide, glulisine; less hypoglycemia with lixisenatide