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The interaction between the organic cation transporter 1 and the serotonin reuptake transporter seems to play a role in metformin intolerance

OCT1, SERT Genes Play Role in Metformin Intolerance

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Intolerance up with low-expressing SERT S* alleles; multiplicative interaction for OCT1, SERT genotypes
The interaction between grapefruit juice and midazolam varies based on grapefruit juice-related characteristics such as the amount of furanocoumarin

Grapefruit-Midazolam Interaction Varies With Juice Characteristics

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Grapefruit juice-drug interaction varies based on amount of furanocoumarin constituents in juice
Use of topical iodine can cause overestimation of blood glucose readings

Topical Iodine Can Cause Overestimation of Blood Glucose

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Case report: 28-year-old pregnant woman with variable glucometer readings after topical iodine use
Twenty-four weeks of empagliflozin + metformin correlates with a significantly greater reduction in hemoglobin A1c compared with once-daily empagliflozin or twice-daily metformin

Greater Drop in Hemoglobin A1c With Empagliflozin + Metformin

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Greater reductions in HbA1c, weight compared to empagliflozin or metformin alone
Inhibiting the sympathetic nervous system by renal denervation improves insulin sensitivity in obese canines

Renal Denervation Ups Insulin Sensitivity in Preclinical Model

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Bilateral renal denervation completely normalizes hepatic insulin sensitivity in obese canines
A culturally-tailored stepwise diabetes prevention program can reduce incidence of diabetes among overweight/obese Asian Indian adults

Stepwise Program Can Reduce Diabetes Incidence

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Culturally-tailored program lowers diabetes incidence in Asian Indian adults with IGT, IFG, or both
For women with polycystic ovary syndrome seeking infertility treatment

Frozen Embryos May Outperform Fresh for Women With PCOS

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Higher rate of live birth, lower risk of ovarian hyperstimulation syndrome
Patients undergoing fertility treatment often suffer symptoms of depression or anxiety

Psychological Toll of Infertility Often Ignored

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Only one-quarter of men and woman said their fertility clinic offered info on mental health services
From 1988 to 2014 there was no change in the overall prevalence of diabetic kidney disease

No Recent Change in Prevalence of Diabetic Kidney Disease

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No change in overall prevalence from 1988 to 2014; decrease in albuminuria, increase in reduced eGFR
For women

Review IDs Determinants of Physical Activity in Women

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Having children in household negatively related to moderate-to-vigorous physical activity