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Resistance to the antilipolytic effect of insulin is increased in obese individuals with normal glucose tolerance

Adipose Tissue Insulin Resistance Up in Obese-NGT, IGT, T2DM

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Progressive decline in β-cell function linked to progressive impairment of free fatty acid suppression
The amplitude of therapeutic revascularization associated with recombinant adeno-associated virus (5 × 1012 viral particles encoding thymosin beta 4) is reduced with diabetes mellitus

Diabetes May Impair Myocardial Proangiogenic Response

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Reduction in amplitude of therapeutic neovascularization via rAAV.Tβ4 in pig model
N-acetylglucosamine/galactosamine is associated with insulin sensitivity

GlycA Linked to Insulin Sensitivity, Independent of CRP

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N-acetylglucosamine/galactosamine independently associated with insulin sensitivity index
Diabetes is associated with increased incidence of conjunctivitis

Diabetes Linked to Increased Incidence of Conjunctivitis

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No correlation for diabetes with other eye infections; glycemic control not linked to any infection
Weight-loss surgery helps severely obese teens maintain weight loss over the long term; however

Very Obese Teens Benefit From Gastric Bypass Over Long Term

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Studies show most maintain significant weight loss over five years, but complications emerge for some
Apolipoprotein CIII and apoCIII-to-apoA1 ratio are correlated with incident type 2 diabetes

Some Apolipoproteins Linked to Incident Type 2 Diabetes

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ApoCIII and apoCIII-to-apoA1 ratio associated with T2D independent of known risk factors
Consumption of single omega-3 is associated with an increased risk of type 2 diabetes

Meta-Analysis Links Omega-3 Fatty Acid Consumption to T2DM

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Composition, ethnicity, trial duration, recruited age all influence effect of omega-3 on T2DM progression
After metformin failure

Sequential Empagliflozin, Linagliptin Diabetes Tx Effective

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Glucose control most probably mediated by effects on alpha- and beta-cell function
Fenofibrate therapy may reduce cardiovascular disease in statin-treated patients with diabetes and dyslipidemia

Fenofibrate May Reduce CVD in Patients With DM, Dyslipidemia

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No reduction in primary outcome for 4,644 ACCORD participants followed for median of 9.7 years
For patients with chronic kidney disease

Metformin Tied to Better Clinical Outcomes in CKD, CHF, CLD

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Reduced all-cause death for chronic kidney disease, congestive heart failure, chronic liver disease