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High-deductible health plans have multiplied in recent years

Many Families Find High Health Care Deductibles Burdensome

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Studies suggest significant out-of-pocket costs may harm low-income and chronically ill patients
A mathematical model can simulate hemoglobin A1c trajectories in type 2 diabetes mellitus models

Mathematical Model Can Simulate HbA1c Progression in T2DM

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Model represents alternative approach to simulate HbA1c trajectories vs. UK Prospective Diabetes Study
Enteroviruses may play a role in the development of at least some cases of type 1 diabetes

Enteroviruses May Be Linked to Autoimmunity Leading to T1DM

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Enteroviruses may induce an autoimmune process against insulin-producing cells in the pancreas
Resistance to the antilipolytic effect of insulin is increased in obese individuals with normal glucose tolerance

Adipose Tissue Insulin Resistance Up in Obese-NGT, IGT, T2DM

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Progressive decline in β-cell function linked to progressive impairment of free fatty acid suppression
The amplitude of therapeutic revascularization associated with recombinant adeno-associated virus (5 × 1012 viral particles encoding thymosin beta 4) is reduced with diabetes mellitus

Diabetes May Impair Myocardial Proangiogenic Response

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Reduction in amplitude of therapeutic neovascularization via rAAV.Tβ4 in pig model
N-acetylglucosamine/galactosamine is associated with insulin sensitivity

GlycA Linked to Insulin Sensitivity, Independent of CRP

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N-acetylglucosamine/galactosamine independently associated with insulin sensitivity index
Diabetes is associated with increased incidence of conjunctivitis

Diabetes Linked to Increased Incidence of Conjunctivitis

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No correlation for diabetes with other eye infections; glycemic control not linked to any infection
Weight-loss surgery helps severely obese teens maintain weight loss over the long term; however

Very Obese Teens Benefit From Gastric Bypass Over Long Term

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Studies show most maintain significant weight loss over five years, but complications emerge for some
Apolipoprotein CIII and apoCIII-to-apoA1 ratio are correlated with incident type 2 diabetes

Some Apolipoproteins Linked to Incident Type 2 Diabetes

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ApoCIII and apoCIII-to-apoA1 ratio associated with T2D independent of known risk factors
Consumption of single omega-3 is associated with an increased risk of type 2 diabetes

Meta-Analysis Links Omega-3 Fatty Acid Consumption to T2DM

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Composition, ethnicity, trial duration, recruited age all influence effect of omega-3 on T2DM progression