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Pioglitazone may not be effective for lowering blood glucose levels

Pioglitazone Has Limited Effect in Lipoatrophic Diabetes

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Slight liver function improvement seen in lipoatrophic diabetes induced by juvenile dermatomyositis
Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets

Insurer Market Power Lowers Providers’ Prices

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Evidence seen for specialists in markets with high provider, insurer concentration
The American College of Physicians does not support the legalization of physician-assisted suicide

ACP Does Not Support Legalization of Assisted Suicide

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Legalization would affect trust in the patient-physician relationship, and in the medical profession
In patients with type 2 diabetes being treated with a dipeptidyl peptidase-4 inhibitor

Anagliptin Effect on LDL in T2DM Via ApoB-100 Synthesis

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Improvement appears mediated, at least in part, through suppression of apoB-100 synthesis
Some adolescents

AHA: Target Organ Damage From HTN Also Seen in Teenagers

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Sixteen percent of teenagers had left ventricular hypertrophy with SBP below the 95th percentile
A multifaceted quality improvement program improves blood pressure control over a six-month period

AHA: Multifaceted Intervention Improves BP Control

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Increase in BP control from 65.6% to 74.8%, with significant increase in control in 12 of 16 practices
For pregnant women with type 1 diabetes

CGM Use in Pregnancy Improves Neonatal Outcomes

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No apparent benefit for continuous glucose monitoring for women planning pregnancy
For patients after an ischemic stroke or transient ischemic attack

Greater Benefit for Pioglitazone in High-Risk Patients Post Stroke

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Patients at higher risk for stroke or MI derive greater benefit from pioglitazone versus low-risk patients
Shorter sleep duration and poor sleep quality are associated with progression of chronic kidney disease

Sleep Quality, Duration Linked to CKD Progression

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Shorter sleep duration, greater sleep fragmentation linked to greater decline in eGFR
Spin in biomedical literature (also referred to as "science hype") is prevalent

‘Science Spin’ Found Prevalent in Biomedical Literature

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Nature of spin varies, with highest variability in prevalence of spin seen in trials