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Retinopathy is associated with accelerated rates of 20-year cognitive decline

Retinopathy Associated With Accelerated Cognitive Decline

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20-year cognitive change is greater with moderate-to-severe retinopathy than no retinopathy
Children exposed to metformin in utero have an increased risk of being overweight at age 4 years

Exposure to Metformin In Utero Ups Risk of Being Overweight

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Findings among children of women with polycystic ovary syndrome on metformin during pregnancy
For adults aged 18 to 64 years with diabetes

Coverage Increased After ACA for Patients With Diabetes

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Health insurance coverage up from 2009 to 2016 among adults with diabetes aged 18 to 64 years
Compared with normal body mass index

Obesity Linked to Increased CVD Morbidity and Mortality

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Overweight adults had similar longevity but longer years lived with CVD compared to normal BMI
Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction in women than men

Increased Adiposity Measures Affect MI Risk More in Women

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Increases in waist circumference, waist-to-hip ratio tied to greater excess risk of MI in women than men
Sleeve gastrectomy is associated with an improvement in glycemia

Sleeve Gastrectomy Linked to Improved Glycemia in Mice

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Sleeve gastrectomy causes improvement in muscle and hepatic insulin sensitivity
For individual patients with type 2 diabetes mellitus

Treatment Effect of Fenofibrate Varies in Patients With T2DM

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Treatment effect is greater in patients with dyslipidemia; absolute risk reduction of 2.15 percent
Trials to evaluate drugs or devices used to treat chronic medical conditions that are published early in the chain of evidence often show an exaggerated treatment effect compared with subsequent trials

Early Studies Often Show Exaggerated Treatment Effect

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Findings based on assessment of trials evaluating drugs, devices to treat chronic medical conditions
Coronary artery bypass grafting is associated with a significant reduction in major adverse cardiac and cerebrovascular events and mortality compared with percutaneous coronary intervention among patients with diabetes mellitus

CABG May Be Best for Patients With DM, LV Dysfunction

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Fewer adverse cardiac, cerebrovascular events, deaths with cardiac artery bypass graft than PCI
Laparoscopic sleeve gastrectomy is associated with a lower rate of gestational diabetes mellitus and excessive fetal growth

Sleeve Gastrectomy Tied to Drop in GDM, Excessive Fetal Growth

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Laparoscopic sleeve gastrectomy also tied to SGA and low birth weight neonates, lower c-section rates