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There is no compelling evidence to indicate health benefits of nonsugar sweetener use on a range of health outcomes

Health Benefits of Nonsugar Sweeteners Uncertain

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However, large systematic review could not rule out harms from nonsugar sweeteners

December 2018 Briefing – Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2018. This roundup includes...
Canagliflozin is not associated with an increased fracture risk versus glucagon-like peptide-1 agonists for middle-aged patients with type 2 diabetes

No Increased Fracture Risk With Canagliflozin in Type 2 Diabetes

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Rate of the primary outcome was similar for canagliflozin, glucagon-like peptide-1 agonist
Three novel loci have been identified for polycystic ovary syndrome

Three Novel Loci Associated With Polycystic Ovary Syndrome ID’d

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Genetic links with obesity, T2DM, lipids suggest shared genetic architecture for PCOS, metabolic traits
For nonindigenous people with type 2 diabetes mellitus in Australia

Incidence of End-Stage Kidney Disease Up in Australia

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Incidence increased for nonindigenous people with type 2 diabetes; greatest increase for under 50s, over 80s
Women born with a low birth weight have an increased risk for pregnancy complications

Pregnancy Complications Up for Women Born at Low Birth Weight

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Risk greatest for women born with birth weight <2,500 g who develop overweight/obesity
A pattern of higher consumption of sugar-sweetened beverages is associated with increased odds of chronic kidney disease

Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

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Odds of CKD up with beverage pattern consisting of higher intake of sweetened soda, fruit drinks, water
For adults with type 2 diabetes initiating second-line antidiabetic medications (ADM)

Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

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Cardiovascular risk increased with sulfonylureas and basal insulin versus newer classes of ADM
The lowest-priced generic drugs are more likely to experience shortages

Low-Priced Generic Drugs Most Likely to Have Shortages

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Shortages associated with modest increases in price, ranging from 6 to 14 percent
Use of primary targeted muscle reinnervation can prevent or reduce pain in below-the-knee amputees

Targeted Muscle Reinnervation Can Reduce Phantom Limb Pain

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Authors report reduction in pain and no symptomatic neuromas in 22 below-the-knee amputees