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Some Americans with type 1 diabetes have cut back on their insulin usage as the cost of the drug nearly doubled over a five-year period.

Insulin Price More Than Doubled in the United States

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Insulin spending rose from about $2,900 in 2012 to about $5,700 in 2016
Poor glycemic control is associated with an increased risk for fracture in patients with type 1 diabetes mellitus but not in patients with type 2 diabetes mellitus

Poor Glycemic Control in Type 1 Diabetes Tied to Fracture Risk

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Fracture risk up with T2DM and current use of rosiglitazone, pioglitazone regardless of glycemic control
Radiographic knee osteoarthritis is associated with an increased risk for mortality from cardiovascular disease

Radiographic Knee Osteoarthritis Tied to Increased Risk for Death

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Risk higher for cardiovascular disease, diabetes, renal mortality; lower risk for cancer mortality
Use of the oral hepatoselective glucokinase activator TTP399 for type 2 diabetes does not cause hypoglycemia and has no detrimental effect on plasma lipids or liver enzymes

Oral Hepatoselective Glucokinase Activator Promising in T2DM

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Clinically significant and sustained reduction in glycated hemoglobin was observed with TTP399
Trained alert dogs can help patients with type 1 diabetes regulate their blood glucose levels

Trained Alert Dogs Can Detect Impending T1DM-Related Events

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In study, individual dogs' performance varied for detecting hypoglycemic episodes, hyperglycemia
A U.S. Food and Drug Administration advisory panel vote on whether to recommend approval of the first oral medication for type 1 diabetes ended in an 8-8 tie Thursday.

FDA Panel Has Tie Vote on New Type 1 Diabetes Drug

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Zynquista is a once-daily pill meant to help type 1 diabetes patients manage their blood glucose levels
Ertugliflozin appears safe and effective at improving long-term glycemic control among adults with type 2 diabetes mellitus inadequately controlled on metformin

Ertugliflozin Seems Safe, Effective for Type 2 Diabetes Treatment

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Improvements seen in HbA1c, fasting glucose, body weight, blood pressure over two years
HFE p.C282Y homozygosity

Hemochromatosis Mutation Linked to Other Morbidity

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Higher rates of at least one incident-linked condition seen in men, women with HFE p.C282Y homozygosity
Achieving a healthy diet from sustainable food systems is feasible but will require considerable shifts toward healthy dietary patterns

Achieving Healthy Diet From Sustainable Food Feasible

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Global adoption of healthy reference diet would reduce morbidity, environmental degradation
Due to the federal government shutdown

FDA Down to 5 Weeks of Funding to Review New Drug Applications

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Agency cannot accept new fees or applications until the shutdown is over