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Metagenomic next-generation sequencing of cerebrospinal fluid obtained from patients with meningitis or encephalitis can improve diagnosis of neurologic infections

Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

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Eight of 13 diagnoses made solely by metagenomic NGS had likely clinical effect, seven guided treatment
Health care has modest effects on extending life expectancy in the United States

Access to Health Care Has Little Impact on Longevity

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Social, behavioral factors account for greater portion of premature mortality than does health care
Among critically ill patients with acute kidney injury

Rapid Fluid Removal May Up Mortality in Critically Ill With AKI

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Higher net ultrafiltration rates with continuous venovenous hemodiafiltration may lower survival
Physician misconduct is being underreported and most Americans do not know where to file a complaint

Survey Indicates Physician Misconduct Is Underreported

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Most Americans do not know that state medical board is best resource to contact in case of complaint
A rapidly cycling work roster is effective in reducing weekly work hours and the occurrence of >16 consecutive-hour shifts as well as improving sleep duration of resident physicians

Rapid Cycling Work Roster Improves Resident Sleep Practices

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In addition, decreases seen in weekly work hours and in the occurrence of >16 consecutive hour shifts
Consumption of dietary supplements

Dietary Supplements May Up Risk for Severe Medical Events

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Increased risk seen in association with supplements sold for muscle building, energy, weight loss
Zerbaxa (ceftolozane and tazobactam) has been approved for a new indication to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia in patients aged 18 years and older

Zerbaxa Approved for Hospital-Acquired Bacterial Pneumonia

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Drug previously approved for treatment of complicated intra-abdominal infections, UTIs

May 2019 Briefing – Critical Care

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Here are what the editors at HealthDay consider to be the most important developments in Critical Care for May 2019. This roundup includes the...
Pressure injuries at the time of admission to an intensive care unit may predict patients at risk for longer hospital stays

Pressure Injuries at Time of ICU Admission Tied to Longer Stays

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Pressure injuries also may have modest association with higher risk for mortality
Peripherally inserted central catheters are frequently used in hospitalized patients with stage 3b or greater chronic kidney disease (estimated glomerular filtration rate

Peripherally Inserted Central Catheters Often Used in CKD

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Despite guidelines, placement of PICCs common in those with advanced chronic kidney disease