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Initial standalone D-dimer testing followed by whole-leg compression ultrasonography in patients with positive D-dimer can safely rule out deep vein thrombosis

Negative D-Dimer Can Safely Rule Out DVT as Standalone Test

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Standalone D-dimer testing followed by whole-leg compression US in positive patients rules out DVT
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of Oct. 12 to 16

Physician’s Briefing Weekly Coronavirus Roundup

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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
Point-of-care testing is associated with large reductions in the time to results for patients presenting with suspected COVID-19

Time to Results Faster With Point-of-Care COVID-19 Testing

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Time to results significantly shorter with QIAstat-Dx Respiratory SARS-CoV-2 Panel than with PCR
Tranexamic acid given in the prehospital setting to injured patients at risk for hemorrhage does not lower 30-day mortality

ACS: Tranexamic Acid No Better Than Placebo After Severe Injury

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Antifibrinolytic agent may lower 30-day mortality when used within one hour of injury, for severe shock
A study to assess whether certain approved or experimental drugs are effective against COVID-19 and warrant testing in large clinical trials has been launched by the U.S. National Institutes of Health (NIH).

NIH Launches Trial of Antibody Drugs Against COVID-19

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The phase 2 trial will assess effectiveness of monoclonal antibodies in conjunction with remdesivir
Sitagliptin treatment added to standard care is associated with reduced mortality and improved clinical outcomes for patients with type 2 diabetes hospitalized with COVID-19

Sitagliptin May Cut Mortality in T2DM Patients With COVID-19

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Sitagliptin at time of hospitalization linked to reduced mortality, improved clinical outcomes
Lack of knowledge is one of the barriers to use of prone positioning for acute respiratory distress syndrome

Lack of Knowledge Barrier to Prone Positioning Use in ARDS

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Implementation strategies developed included educational outreach, learning collaborative
Black and Mixed/Other ethnicity are independently associated with greater hospital admission risk due to COVID-19 but are not associated with in-hospital mortality risk

Black Race Tied to COVID-19 Admissions, but Not Deaths

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In-hospital mortality higher for Asian patients, despite lower risk for hospital admission
Enrollment in a study testing an experimental antibody therapy against COVID-19 has been paused by independent monitors.

COVID-19 Antibody Treatment Study Paused

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ACTIV-3 study, testing use of an antibody therapy with remdesivir, paused 'out of an abundance of caution'
Current angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use is associated with a slightly lower mortality risk in patients hospitalized with influenza or pneumonia

Certain HTN Meds May Cut Deaths From Influenza, Pneumonia

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Use of ACE-I/ARB versus nonuse linked to lower mortality for those hospitalized with flu, pneumonia