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Serum growth differentiation factor 15 levels are associated with coronary artery disease

Growth Differentiation Factor 15 Levels Linked to CAD

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Serum levels significantly increased in coronary artery disease patients versus healthy controls
From 1973-1974 to 2009-2010 there were changes in the geographic patterns of heart disease mortality

Geographic Variation in Heart Disease Mortality Over Time

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From 1973-1974 to 2009-2010, shift in concentration of high-rate counties from Northeast to Deep South
Patients with persistent atrial fibrillation from the onset have distinct demographics and poorer clinical outcome

Distinct Demographics for Persistent A-Fib From Onset

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Specific demographics, underlying diffuse substrate disease, and poorer clinical outcome
Incretin-based drugs are not associated with increased risk of hospitalization for heart failure

Incretin-Based Drugs Don’t Up Heart Failure Hospitalization Risk

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Rate of hospitalization for heart failure not up among those with or without a history of heart failure
Intrabody

ACC: Leadless Pacemaker, Subcutaneous ICD Feasible

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First proof of concept of successful wireless device-to-device communication in rhythm management
Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies may represent a promising treatment option for acute coronary syndrome

PCSK9 Monoclonal Antibodies Show Promise in ACS

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Suggestion of dual antidyslipidemic and plaque-stabilizing effects in the early phase of ACS
Intrabody

ACC: Leadless Pacemaker, Subcutaneous ICD Feasible

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First proof of concept of successful wireless device-to-device communication in rhythm management
Switching from prasugrel to ticagrelor is associated with a transient increase in platelet inhibition

ACC: Higher Platelet Inhibition With Switch to Ticagrelor

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Switching from prasugrel to ticagrelor linked to transiently increased levels of platelet inhibition
Selective serotonin reuptake inhibitors don't appear to raise cardiovascular risk among young and middle-age patients

SSRIs Do Not Appear to Increase Cardiovascular Risk

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Fluoxetine actually seems to protect against myocardial infarction, researchers say
Crushed prasugrel correlates with faster drug absorption for patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

ACC: Faster Absorption of Crushed Prasugrel in STEMI

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Crushed prasugrel led to reduction in P2Y12 reaction units for up to four hours post-loading dose