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In 2016 the age-standardized prevalence of insufficient physical activity was 27.5 percent

Global Prevalence of Insufficient Activity 27.5 Percent

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Levels of insufficient physical activity stable between 2001, 2016; increase seen in high-income countries
Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge

No Clear Benefit for Rivaroxaban After Hospital Discharge

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Incidence of major bleeding low with rivaroxaban, but clot risk not lower
Half of trials on the European Union Clinical Trials Register are non-compliant with the European Commission's requirement that all trials post results to the registry within 12 month of completion

Compliance With Requirement to Report Results on EUCTR Is Poor

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Half of trials on European Union Clinical Trials Register are non-compliant with requirements
Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage

Drug Prices Increase More Than Expected After Shortages

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Expected price increase 20 percent for all drugs after shortage versus 9 percent in absence of shortage
Use of medical scribes is associated with decreased physician documentation burden

Scribes Improve Physician Workflow, Patient Interaction

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Scribes lower EHR documentation burden for doctors and increase time spent interacting with patients
In patients with transthyretin amyloid cardiomyopathy

Tafamidis Treats Transthyretin Amyloid Cardiomyopathy

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Reduces all-cause mortality, cardiovascular-related hospitalizations compared with placebo
Clinicians advising families living overseas in highly polluted settings should understand their patients' concerns and have a network of resources to draw upon for guidance

Tips for Advising Patients Living in Highly Polluted Settings

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Guidance focuses on Americans posted in overseas settings with high ambient levels of air pollution
For high-risk patients with implantable cardioverter-defibrillators (ICDs)

Ranolazine Doesn’t Cut VT, VF, Death in High-Risk ICD Patients

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No significant reduction in VT or VF or death risk for patients with implantable cardioverter-defibrillators
For commonly prescribed cardiovascular drugs

Drug Prices Seem Not to Be Influenced by Their Value

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Incremental cost-effectiveness ratio of 30 heart medications varied from cost-saving to costly
For patients with advanced heart failure who are listed for transplantation

Model Estimates Mortality in Patients Waiting for Hearts

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Neurologic events, new requirement for dialysis, respiratory complications yield updated estimates