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The 99th centile of high-sensitivity cardiac troponin I concentration is substantially higher in a hospital population than the manufacturer's recommended upper limit of normal

Troponin Assay Confusion May Cause Misdiagnosis of Acute MI

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Overall, 5.4 percent of 20,000 patients had high-sensitivity troponin I concentration >40 ng/L
There is considerable concern regarding the potential negative impact that electronic cigarettes and other new products may have on ending all tobacco use and nicotine addiction

E-Cigarettes May Threaten Goal of Achieving Tobacco Endgame

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Concern increasing that use of newer tobacco products may catalyze transition to tobacco products, drugs
Most Americans report having excellent or good health and have a usual place to go for medical care

CDC: Most Americans Report Excellent, Good Health

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Most health measures remained stable from 2017; percent of adults who have been tested for HIV increased
Bempedoic acid

Adding Bempedoic Acid to Statin Therapy Reduces LDL Cholesterol

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Genetic variants mimicking effect of ATP citrate lyase inhibitors, statins lower LDL-C in same way
The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb

Head of National Cancer Institute Named Acting FDA Commissioner

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Current commissioner, Scott Gottlieb, will be stepping down in April
The U.S. Food and Drug Administration on Tuesday approved a new generic version of the high blood pressure/heart failure drug valsartan

FDA Approves New Generic Valsartan to Ease Shortage

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Certain lots of valsartan recalled due to contamination with trace amounts of nitrosamine
Estimated age based on exercise stress testing performance may be a better predictor of mortality than chronological age

Stress Test-Based Physiological Age May Be Superior Mortality Predictor

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Physiological age based on exercise stress testing performance better predictor than chronological age
Disability-adjusted life year rates for out-of-hospital cardiac arrest are 1

Out-of-Hospital Cardiac Arrest Third Leading Cause of DALYs

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Disability-adjusted life year rates 1,347 per 100,000 individuals, behind ischemic heart disease, back pain
Poor cardiorespiratory fitness is strongly associated with coronary heart disease in a low-risk population

Cardiorespiratory Fitness Tied to Coronary Heart Disease Risk

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Association between VO2peak and coronary heart disease crosses the fitness continuum
A history of weight cycling

History of Cycling Weight May Up Risk for Heart Disease in Women

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Yo-yo dieting associations with cardiovascular disease stronger in women with no pregnancy history