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Emergency medical diseases contribute to about half of mortality and two-fifths of the burden of diseases globally

Emergency Medical Diseases Account for About Half of Mortality

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31 emergency medical diseases contribute 50.7 percent of global mortality in 195 countries
The U.S. Food and Drug Administration this week announced three new efforts to protect patients from malfunctions

FDA Announces New Steps to Reduce Risks Tied to Surgical Staplers

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Agency proposing higher classification of surgical staplers that will require premarket notification clearance
Cardiovascular risk screening intervals based on risk category-specific progression rates would perform better and improve cost-effectiveness compared with established five-year screening intervals

Risk-Based Screening Improves Cardiovascular Disease Prevention

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Benefits seen for prevention of major cardiovascular events, higher quality-adjusted life years
Consumption of sleeping pills is linked to a subsequent increase in the number of antihypertensive drugs taken among older adults

Sleeping Pill Use Tied to Greater Need for BP Meds in Older Adults

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But no association observed between sleep duration or quality and change in BP drug use
For older patients with acute myocardial infarction

PCI Beneficial for All Categories of Older AMI Patients

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PCI linked to improved survival versus medical therapy for young-old, middle-old, and old-old patients
Early aortic valve replacement may improve survival in patients with severe

In Severe, Asymptomatic Aortic Stenosis, Early Surgery May Help

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Patients undergoing aortic valve replacement within a year of diagnosis appear to benefit most
A risk model has been developed and validated for hospital readmission within 30 days after acute myocardial infarction in older patients and has demonstrated moderate performance

Risk Model Developed for Readmission After AMI in Seniors

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Strongest predictor of 30-day readmission among adults ≥75 years is impaired functional mobility
High resting heart rate is associated with an increased risk for death and cardiovascular events in men

High Resting Heart Rate Linked to Increased Cardiac Risk in Men

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Risk for all-cause death, CVD, CHD increased with RHR >75 and with increase in RHR over time
Children reclassified to higher blood pressure categories based on 2017 pediatric hypertension definitions are at increased risk for developing adverse cardiometabolic outcomes

Cardiometabolic Risk Better ID’d in Children Reclassified to Higher BP

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Likelihood of developing adult HTN, MetS, LVH increased for children reclassified with 2017 guidelines
Moderate-to-vigorous physical activity equivalent to meeting current recommendations attenuates the association of sitting with all-cause and cardiovascular disease mortality

Moderate/Vigorous Exercise Attenuates Risks of Sitting

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Sitting time linked to all-cause, CVD mortality in least active adults; MVPA can attenuate these links