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Report Questions Benefit of FDA Accelerated Approval Pathway

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112 of the 253 authorized drugs have not been confirmed as clinically effective; 24 of these have been on market more than five years

U.S. Medical Debt High, but Varies Geographically

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Debt higher in the South, in lowest income ZIP codes, and in states without Medicaid expansion

Patterns Studied for Alcohol Intake, Outcomes in Patients With CVD

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Relative to nondrinkers, a J-shaped curve was seen for all-cause mortality, CV mortality, and CV events in drinkers with preexisting CVD

Metabolic Syndrome Linked to Increased Risk for Stroke Recurrence

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Low levels of HDL cholesterol and having two or more components of metabolic syndrome predict recurrence

Long-Term Complications Common With Youth-Onset T2DM

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Risk factors for development of complications include minority race or ethnic group, hyperglycemia, hypertension, dyslipidemia

Donor Drug Use Not Tied to Survival for Heart Transplant Recipients

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And risk for posttransplant death decreasing despite drug overdose, hepatitis C-positive donors contributing to donor risk

Return to Play Seems Safe for Most Athletes With Long QT Syndrome

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No genetic heart disease-sports-associated mortality seen in 2,056 combined years of follow-up

Inequalities Found With U.S. Family and Medical Leave Act Requirement

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Women disproportionately excluded in minimum hours requirement; tenure requirement excludes Blacks, indigenous, multiracial workers

~40 Percent of Incident Heart Failure Diagnoses Occur in Acute Care

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46 percent of those diagnosed in acute care had potential heart failure symptoms in previous six months

Pfizer, Moderna to Expand Vaccine Studies in Young Children

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Companies made the move after FDA told them that the initial size and scope of their studies were not enough to detect the rare side effects