Report Questions Benefit of FDA Accelerated Approval Pathway
112 of the 253 authorized drugs have not been confirmed as clinically effective; 24 of these have been on market more than five years
U.S. Medical Debt High, but Varies Geographically
Debt higher in the South, in lowest income ZIP codes, and in states without Medicaid expansion
Patterns Studied for Alcohol Intake, Outcomes in Patients With CVD
Relative to nondrinkers, a J-shaped curve was seen for all-cause mortality, CV mortality, and CV events in drinkers with preexisting CVD
Metabolic Syndrome Linked to Increased Risk for Stroke Recurrence
Low levels of HDL cholesterol and having two or more components of metabolic syndrome predict recurrence
Long-Term Complications Common With Youth-Onset T2DM
Risk factors for development of complications include minority race or ethnic group, hyperglycemia, hypertension, dyslipidemia
Donor Drug Use Not Tied to Survival for Heart Transplant Recipients
And risk for posttransplant death decreasing despite drug overdose, hepatitis C-positive donors contributing to donor risk
Return to Play Seems Safe for Most Athletes With Long QT Syndrome
No genetic heart disease-sports-associated mortality seen in 2,056 combined years of follow-up
Inequalities Found With U.S. Family and Medical Leave Act Requirement
Women disproportionately excluded in minimum hours requirement; tenure requirement excludes Blacks, indigenous, multiracial workers
~40 Percent of Incident Heart Failure Diagnoses Occur in Acute Care
46 percent of those diagnosed in acute care had potential heart failure symptoms in previous six months
Pfizer, Moderna to Expand Vaccine Studies in Young Children
Companies made the move after FDA told them that the initial size and scope of their studies were not enough to detect the rare side effects