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Omalizumab appears to be highly effective for the management of severe allergic asthma

Omalizumab Highly Effective for Severe Allergic Asthma

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Review of "real-life" studies shows improvements across objective and subjective burden of illness
Conventional non-pharmacologic and pharmacologic options for the management of opioid-induced constipation in pregnancy are often ineffective or cause potentially troublesome adverse effects

Opioid-Related Constipation Tx Suboptimal in Pregnancy

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PAMORA strategy appears to safe with superior effectiveness
About 20 percent of patients administered fresh frozen plasma (FFP) to reverse warfarin anticoagulation develop pulmonary complications

Dose-Linked Pulmonary Complications After FFP Infusion

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In warfarin reversal, highest risk with more than three units of fresh frozen plasma
All adults and teens at increased risk for syphilis should be screened for the sexually transmitted disease

USPSTF: Screen All Teens, Adults at Risk for Syphilis

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Proposed recommendation dovetails with surge in U.S. cases of the sexually transmitted disease
Better screening and lifestyle changes have helped to reduce the prevalence of common cancers in many high-income countries

Uptake of ‘Western Lifestyle’ Tied to Rising Cancer Rates

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Lower-income countries have rising rates of same cancers common in high-income countries
A combination of immune-modulatory in situ gene therapy and intensity-modulated radiotherapy is highly effective in treating prostate cancer

‘Suicide Gene Therapy’ Plus Radiation Effective in Prostate CA

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Immunomodulatory in situ gene tx/IMRT with or without hormonal tx deemed feasible, safe
Antidepressant use during the second and third trimesters of pregnancy may increase the risk for autism spectrum disorder in offspring

Antidepressant Use in Pregnancy Tied to ASD Risk in Offspring

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Antidepressant use in second or third trimester linked to 87 percent increased ASD risk
Mental disorders seem to be associated with chronic pain in adolescents

Mental Disorders Associated With Chronic Pain in Teens

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Most substantial temporal links for affective, anxiety, and behavior disorders prior to chronic pain
A recent survey of pediatric anesthesia programs at teaching institutions in the United States highlights the need for improvements in training

Neurotoxicity of Anesthesia in Children Needs to Be Addressed

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Survey suggests need for improvements in clinical practice, training, and communication on this topic
High levels of perceived stress could be a risk factor for cognitive impairment and Alzheimer's disease

Perceived Stress May Increase Risk of Cognitive Decline

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Adults who perceived themselves to be under the most stress had 30 percent greater risk