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For patients with rheumatoid arthritis and a first non-tumor necrosis factor inhibitor failure

Tocilizumab Treats Rheumatoid Arthritis After Non-TNFi Failure

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Better efficacy for tocilizumab versus abatacept and rituximab in patients with first non-TNFi failure
Segmental vitiligo compromises motor nerves in the lesional limbs

Motor Nerve Conduction Velocity Slowed in Segmental Vitiligo

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Motor nerves in the lesional limbs compromised by SV, particularly when the disease is at the stable stage
The burden of hepatitis C virus and associated disease is projected to remain considerable even in the era of oral direct-acting antivirals

Burden of Hep C Virus Substantial Despite Oral Antiviral Therapy

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In the next 35 years, 320,000 patients expected to die, 157,000 to develop hepatocellular carcinoma
More than 3 percent of preterm births nationally can be attributed to exposure to particulate matter <2.5 microns in diameter

>3% of Preterm Births Attributed to Exposure to Particulate Matter

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Attributable preterm birth costs estimated at $4.33 billion, of which $760 million spent on medical care
Development of islet autoimmunity and multiple islet autoantibodies appears to be related to weight z-scores at age 12 months

Higher Weight in First Year May Up Risk of Islet Autoimmunity

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Development of islet autoimmunity linked to weight z-scores at 12, but not 24 or 36, months of age
A new prediction rule may inform which patients will see a benefit or harm from dual antiplatelet therapy beyond one year after percutaneous coronary intervention

Tool Guides Duration of Dual Antiplatelet Therapy After PCI

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For patients without major bleed, ischemic event at one year after percutaneous coronary intervention
More graduate medical education should be financed to meet the needs of children and the pediatric workforce

AAP Calls for More Funds for Graduate Education in Pediatrics

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Increase in funding of GME positions recommended to address pediatrician workforce needs
More than one in three older adults are given at least one potentially inappropriate prescription at the time of hospital discharge

Improper Prescribing Common at Hospital Discharge of Seniors

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Finding among older adults discharged from cardiology, internal medicine services
Antipsychotic medications do not appear to be effective for preventing or treating delirium in adult medical or surgical inpatients

Antipsychotics Not Effective for Delirium in Hospitalized Patients

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No significant effect found for preventing or treating delirium during hospitalization
Mortality and reoperation rates are very low among working-age patients with severe gastroesophageal reflux disease undergoing primary laparoscopic fundoplication

Mortality Low for Laparoscopic Surgery in Severe GERD

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For patients with severe GERD, low rates of 90- and 30-day mortality and 90-day reoperation