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Recommendations have been developed for the diagnosis and management of multiple myeloma-related renal impairment; the guidelines were published online March 14 in the Journal of Clinical Oncology.

Recommendations Issued for Myeloma-Tied Renal Impairment

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Practical recommendations developed for diagnosis and management of renal impairment
In U.S. adolescents

Off-Label Use of Metformin Common in U.S. Adolescents

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Analyses of three databases show use for metabolic syndrome, PCOS, and obesity
For subjects at risk of aspirin-associated upper gastrointestinal events

PA32540 Safe for Patients at Risk of Aspirin-Linked Upper GI Events

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Long-term, once-daily enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg is safe
Tai chi and other traditional Chinese exercises may benefit patients with cardiovascular disease

Practicing Tai Chi Could Improve Cardiovascular Health

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Traditional Chinese exercises might reduce depression, improve quality of life for heart patients
Obese women taking oral contraceptives may be nearly 30 times more likely to develop cerebral venous thrombosis

Cerebral Venous Thrombosis Risk Up in Obese Women on OCPs

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Better counseling of obese women needed, including consideration of non-hormonal contraceptives
Giving one dose of the varicella vaccine at age 1 and a second dose at ages 4 to 6 is nearly 100 percent effective in preventing varicella

Two-Dose Varicella Vaccine Offers Improved Protection

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Adding second inoculation at ages 4 to 6 is almost 100 percent effective
Negotiations to increase payment from insurance companies can be extremely difficult

Guidance Offered for Negotiating Higher Rates From Payers

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Compiling the information needed to approach insurance companies is time consuming
Riboflavin-ultraviolet A collagen crosslinking used in photoactivated chromophore for infectious keratitis has bactericidal efficacy for both antibiotic resistant and non-resistant bacteria

UVA-Riboflavin Cuts Antibiotic-Resistant, Non-Resistant Bacteria

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For photoactivated chromophore for infectious keratitis using riboflavin-UVA collagen crosslinking
Serotonin appears to be involved in autoimmune arthritis through Th17 immunity and bone resorption

Serotonin Directly Implicated in Rheumatoid Arthritis

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Serotonin shows fundamental role through regulation of the Th17/T-regulatory cell balance
U.S. health officials on Friday gave tentative approval to a field test in the Florida Keys of mosquitoes genetically modified to help curb the spread of the Zika virus.

FDA Gives Tentative Approval to Tests of Gene-Modified Mosquitos

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Agency says testing the insects in Florida Keys poses little risk to people, animals, the environment